{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["22(1)"],"submitter":["Li MJ"],"pubmed_abstract":["<h4>Objective</h4>The prevalence and mortality of cardiovascular diseases remain ranked first worldwide. Myocardial infarction (MI) is the central cause of death from cardiovascular diseases, seriously endangering human health. The clinical implication of toll-like receptor 2 (TLR2) remains contradictory, and its mechanism is still unknown. Hence, the objective of this study was to elucidate the clinical value and molecular mechanism of TLR2 in MI.<h4>Methods</h4>All high-throughput datasets and eligible literature were screened, and the expression levels of TLR2 were collected from the MI. The integrated expression level of TLR2 was displayed by calculating the standardized mean difference (SMD) and the area under the curve (AUC) of the summary receiver operating characteristic curve (sRO"],"journal":["BMC cardiovascular disorders"],"pagination":["314"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9287878"],"repository":["biostudies-literature"],"pubmed_title":["Clinical assessment and molecular mechanism of the upregulation of Toll-like receptor 2 (TLR2) in myocardial infarction."],"pmcid":["PMC9287878"],"pubmed_authors":["Pan HB","Yan SB","Huang ZG","Yang Z","Li DM","Tang YL","Dong H","Chen G","Pan YF","Li MJ"],"additional_accession":[]},"is_claimable":false,"name":"Clinical assessment and molecular mechanism of the upregulation of Toll-like receptor 2 (TLR2) in myocardial infarction.","description":"<h4>Objective</h4>The prevalence and mortality of cardiovascular diseases remain ranked first worldwide. Myocardial infarction (MI) is the central cause of death from cardiovascular diseases, seriously endangering human health. The clinical implication of toll-like receptor 2 (TLR2) remains contradictory, and its mechanism is still unknown. Hence, the objective of this study was to elucidate the clinical value and molecular mechanism of TLR2 in MI.<h4>Methods</h4>All high-throughput datasets and eligible literature were screened, and the expression levels of TLR2 were collected from the MI. The integrated expression level of TLR2 was displayed by calculating the standardized mean difference (SMD) and the area under the curve (AUC) of the summary receiver operating characteristic curve (sRO","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jul","modification":"2025-04-18T23:00:33.11Z","creation":"2024-12-04T12:10:19.374Z"},"accession":"S-EPMC9287878","cross_references":{"pubmed":["35840880"],"doi":["10.1186/s12872-022-02754-y"]}}