biostudies-literatureUnknown23(1)Fu W<h4>Background</h4> Ammonium is an important raw material for biomolecules and life activities, and the toxicity of ammonium is also an important ecological and agricultural issue. Ammonium toxicity in yeast has only recently been discovered, and information on its mechanism is limited. In recent years, environmental pollution caused by nitrogen-containing wastewater has been increasing. In addition, the use of yeast in bioreactors to produce nitrogen-containing compounds has been developed. Therefore, research on resistance mechanisms that allow yeast to grow under conditions of high concentrations of ammonium has become more and more important. <h4>Results</h4> To further understand the resistance mechanism of yeast to grow under high concentration of ammonium, we used NH4Cl to screen a BMC genomicshttps://www.ebi.ac.uk/biostudies/studies/S-EPMC9287935biostudies-literatureGenome-wide identification of resistance genes and transcriptome regulation in yeast to accommodate ammonium toxicityPMC9287935Jin XCao XZhang JLi DFu WLiu BAn TZhao HfalseGenome-wide identification of resistance genes and transcriptome regulation in yeast to accommodate ammonium toxicity<h4>Background</h4> Ammonium is an important raw material for biomolecules and life activities, and the toxicity of ammonium is also an important ecological and agricultural issue. Ammonium toxicity in yeast has only recently been discovered, and information on its mechanism is limited. In recent years, environmental pollution caused by nitrogen-containing wastewater has been increasing. In addition, the use of yeast in bioreactors to produce nitrogen-containing compounds has been developed. Therefore, research on resistance mechanisms that allow yeast to grow under conditions of high concentrations of ammonium has become more and more important. <h4>Results</h4> To further understand the resistance mechanism of yeast to grow under high concentration of ammonium, we used NH4Cl to screen a 2022-01-01T00:00:00Z2022 Jan2025-04-19T23:25:19.968Z2025-02-19T03:22:39.683ZS-EPMC9287935