biostudies-literatureLee YCthe Ministry of Science and Technologythe National Health Research Institutes566https://www.ebi.ac.uk/biostudies/studies/S-EPMC9287972biostudies-literatureUnknown23(1)<h4>Background</h4>Combining robotic therapy (RT) with task-oriented therapy is an emerging strategy to facilitate motor relearning in stroke rehabilitation. This study protocol will compare novel rehabilitation regimens that use bilateral RT as a priming technique to augment two task-oriented therapies: mirror therapy (MT) and bilateral arm training (BAT) with a control intervention: RT combined with impairment-oriented training (IOT).<h4>Methods</h4>This single-blind, randomized, comparative efficacy study will involve 96 participants with chronic stroke. Participants will be randomized into bilateral RT+MT, bilateral RT+BAT, and bilateral RT+IOT groups and receive 18 intervention sessions (90 min/day, 3 d/week for 6 weeks). The outcomes will include the Fugl-Meyer Assessment, Stroke ImpTrialsEffects of robotic priming of bilateral arm training, mirror therapy, and impairment-oriented training on sensorimotor and daily functions in patients with chronic stroke: study protocol of a single-blind, randomized controlled trial.PMC9287972NHRI-EX109-10929PIMOST 108-2314-B-002-165-MY3Liu TXYeh YPChang YJHsu WLLin KCWu YHLee YCLi YCLiu CTLee YYChang CYao GChu HTfalseEffects of robotic priming of bilateral arm training, mirror therapy, and impairment-oriented training on sensorimotor and daily functions in patients with chronic stroke: study protocol of a single-blind, randomized controlled trial.<h4>Background</h4>Combining robotic therapy (RT) with task-oriented therapy is an emerging strategy to facilitate motor relearning in stroke rehabilitation. This study protocol will compare novel rehabilitation regimens that use bilateral RT as a priming technique to augment two task-oriented therapies: mirror therapy (MT) and bilateral arm training (BAT) with a control intervention: RT combined with impairment-oriented training (IOT).<h4>Methods</h4>This single-blind, randomized, comparative efficacy study will involve 96 participants with chronic stroke. Participants will be randomized into bilateral RT+MT, bilateral RT+BAT, and bilateral RT+IOT groups and receive 18 intervention sessions (90 min/day, 3 d/week for 6 weeks). The outcomes will include the Fugl-Meyer Assessment, Stroke Imp2022-01-01T00:00:00Z2022 Jul2025-04-25T18:09:16.661Z2024-11-15T15:47:00.546ZS-EPMC92879723584105610.1186/s13063-022-06498-0