biostudies-literatureHeiderscheit BCNFL Foundation128https://www.ebi.ac.uk/biostudies/studies/S-EPMC9288010biostudies-literatureUnknown14(1)<h4>Background</h4>The etiology of hamstring strain injury (HSI) in American football is multi-factorial and understanding these risk factors is paramount to developing predictive models and guiding prevention and rehabilitation strategies. Many player-games are lost due to the lack of a clear understanding of risk factors and the absence of effective methods to minimize re-injury. This paper describes the protocol that will be followed to develop the HAMstring InjuRy (HAMIR) index risk prediction models for HSI and re-injury based on morphological, architectural, biomechanical and clinical factors in National Collegiate Athletic Association Division I collegiate football players.<h4>Methods</h4>A 3-year, prospective study will be conducted involving collegiate football student-athletes atBMC sports science, medicine & rehabilitationThe development of a HAMstring InjuRy (HAMIR) index to mitigate injury risk through innovative imaging, biomechanics, and data analytics: protocol for an observational cohort study.PMC9288010AAJ5998 MSN249213Sanfilippo JFabian KCostigan KTaylor TWilson JCiocca MBruening DRemington ESnee SBerkoff DMartin JTaylor FBedi ATimmins RAllred DWoodhouse DMeyer CTanaka CFeng XMagargee SSund SManiar NSponbeck JKOpar DHeidt DBeutler ALin YCSmedley AALisee CJohnson AWTitter JBlemker SSKliethermes SABerkowitz JMortensen BBuckley CLee KHAMIR Study GroupHammer ECousins MRiem LChoudhari MDuCharme OOliaro SBaer GLund BRoss LMoll MHeiderscheit BCPietrosimone BFeller HHickey JStiffler-Joachim MREberhardt DHart JDrew SBlackburn TNguyen CCampbell DBirchmeier TMcCoy NNguyen AWest RAllen SLennon AMincberg DfalseThe development of a HAMstring InjuRy (HAMIR) index to mitigate injury risk through innovative imaging, biomechanics, and data analytics: protocol for an observational cohort study.<h4>Background</h4>The etiology of hamstring strain injury (HSI) in American football is multi-factorial and understanding these risk factors is paramount to developing predictive models and guiding prevention and rehabilitation strategies. Many player-games are lost due to the lack of a clear understanding of risk factors and the absence of effective methods to minimize re-injury. This paper describes the protocol that will be followed to develop the HAMstring InjuRy (HAMIR) index risk prediction models for HSI and re-injury based on morphological, architectural, biomechanical and clinical factors in National Collegiate Athletic Association Division I collegiate football players.<h4>Methods</h4>A 3-year, prospective study will be conducted involving collegiate football student-athletes at2022-01-01T00:00:00Z2022 Jul2025-04-22T21:36:04.265Z2024-11-12T21:22:22.465ZS-EPMC92880103584105310.1186/s13102-022-00520-3