{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2022"],"submitter":["Yao Q"],"pubmed_abstract":["<h4>Background</h4>The expression of HAUS Augmin-like complex subunit 1 (HAUS1), a protein-coding gene, is low in normal samples among various cancers with pan-cancer analysis. The depletion of HAUS1 in cells decreases the G2/M cell compartment and induces apoptosis. However, the detailed expression pattern of HAUS1 and its correlation with immune infiltration in glioma (LGG and GBM) (LGG: low-grade glioma; GBM: glioblastoma) remain unknown. Therefore, in this study, we examined the role and prognostic value of HAUS1 in glioma.<h4>Methods</h4>Transcriptional expression data of HAUS1 were collected from the CGGA and TCGA databases. The Kaplan-Meier analysis, univariate and multivariate Cox analyses, and receiver operating characteristic (ROC) curves were used to analyse the clinical signifi"],"journal":["Journal of oncology"],"pagination":["8027686"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9296284"],"repository":["biostudies-literature"],"pubmed_title":["HAUS Augmin-Like Complex Subunit 1 Influences Tumour Microenvironment and Prognostic Outcomes in Glioma."],"pmcid":["PMC9296284"],"pubmed_authors":["Shen J","Chen J","Ge X","Lu Z","Yao Q","Shi J"],"additional_accession":[]},"is_claimable":false,"name":"HAUS Augmin-Like Complex Subunit 1 Influences Tumour Microenvironment and Prognostic Outcomes in Glioma.","description":"<h4>Background</h4>The expression of HAUS Augmin-like complex subunit 1 (HAUS1), a protein-coding gene, is low in normal samples among various cancers with pan-cancer analysis. The depletion of HAUS1 in cells decreases the G2/M cell compartment and induces apoptosis. However, the detailed expression pattern of HAUS1 and its correlation with immune infiltration in glioma (LGG and GBM) (LGG: low-grade glioma; GBM: glioblastoma) remain unknown. Therefore, in this study, we examined the role and prognostic value of HAUS1 in glioma.<h4>Methods</h4>Transcriptional expression data of HAUS1 were collected from the CGGA and TCGA databases. The Kaplan-Meier analysis, univariate and multivariate Cox analyses, and receiver operating characteristic (ROC) curves were used to analyse the clinical signifi","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-26T21:43:43.271Z","creation":"2022-08-08T09:51:31.089Z"},"accession":"S-EPMC9296284","cross_references":{"pubmed":["35865089"],"doi":["10.1155/2022/8027686"]}}