{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["127(2)"],"submitter":["Pang X"],"pubmed_abstract":["<h4>Background</h4>The potential of using magnetic resonance image tumour-regression grading (MRI-TRG) system to predict pathological TRG is debatable for locally advanced rectal cancer treated by neoadjuvant radiochemotherapy.<h4>Methods</h4>Referring to the American Joint Committee on Cancer/College of American Pathologists (AJCC/CAP) TRG classification scheme, a new four-category MRI-TRG system based on the volumetric analysis of the residual tumour and radiochemotherapy induced anorectal fibrosis was established. The agreement between them was evaluated by Kendall's tau-b test, while Kaplan-Meier analysis was used to calculate survival outcomes.<h4>Results</h4>In total, 1033 patients were included. Good agreement between MRI-TRG and AJCC/CAP TRG classifications was observed (k = 0.671)"],"journal":["British journal of cancer"],"pagination":["268-277"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9296509"],"repository":["biostudies-literature"],"pubmed_title":["A new magnetic resonance imaging tumour response grading scheme for locally advanced rectal cancer."],"pmcid":["PMC9296509"],"pubmed_authors":["Zheng J","Yu L","Chen H","Wan X","Pang X","Xie P","Meng X"],"additional_accession":[]},"is_claimable":false,"name":"A new magnetic resonance imaging tumour response grading scheme for locally advanced rectal cancer.","description":"<h4>Background</h4>The potential of using magnetic resonance image tumour-regression grading (MRI-TRG) system to predict pathological TRG is debatable for locally advanced rectal cancer treated by neoadjuvant radiochemotherapy.<h4>Methods</h4>Referring to the American Joint Committee on Cancer/College of American Pathologists (AJCC/CAP) TRG classification scheme, a new four-category MRI-TRG system based on the volumetric analysis of the residual tumour and radiochemotherapy induced anorectal fibrosis was established. The agreement between them was evaluated by Kendall's tau-b test, while Kaplan-Meier analysis was used to calculate survival outcomes.<h4>Results</h4>In total, 1033 patients were included. Good agreement between MRI-TRG and AJCC/CAP TRG classifications was observed (k = 0.671)","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jul","modification":"2025-04-22T13:05:36.868Z","creation":"2025-04-06T00:32:16.041Z"},"accession":"S-EPMC9296509","cross_references":{"pubmed":["35388140"],"doi":["10.1038/s41416-022-01801-x"]}}