biostudies-literaturePark DHKorea Medical Device Development Fund funded by the Korean governmentBasic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of EducationKorea University Ansan HospitalKorea Medical Device Development Fund funded by the Korean government (the Ministry of Science and ICT, Industry and Energy, Health & Welfare, and Food and Drug Safety)12441https://www.ebi.ac.uk/biostudies/studies/S-EPMC9300604biostudies-literatureUnknown12(1)Virtual reality (VR) has recently been used as a clinical treatment because it can efficiently simulate situations that are difficult to control in real-world settings. In our study, we assessed the potential of VR in patients with chronic subjective tinnitus. An evaluation of its clinical benefits was performed based on analyses of patient electroencephalograms (EEGs) and by questionnaire responses after 6-8 weeks of patient involvement in our VR-based alleviation program. Clinical trials were performed at a tertiary academic hospital. Nineteen patients (aged 33-64 years) who visited our hospital with chronic subjective tinnitus over 3 months were enrolled in the study. The intervention consisted of trashing the tinnitus avatar in VR. We expected that the patients would have the subjectivScientific reportsA clinical trial of a patient-customized virtual reality intervention for tinnitus.PMC9300604No. 2018R1D1A1A02085645NTIS 9991006786, KMDF_PR_20200901_0113Kim SKim HNHan MAan HKim KPark DHKim JChoi JHan SSPark SfalseA clinical trial of a patient-customized virtual reality intervention for tinnitus.Virtual reality (VR) has recently been used as a clinical treatment because it can efficiently simulate situations that are difficult to control in real-world settings. In our study, we assessed the potential of VR in patients with chronic subjective tinnitus. An evaluation of its clinical benefits was performed based on analyses of patient electroencephalograms (EEGs) and by questionnaire responses after 6-8 weeks of patient involvement in our VR-based alleviation program. Clinical trials were performed at a tertiary academic hospital. Nineteen patients (aged 33-64 years) who visited our hospital with chronic subjective tinnitus over 3 months were enrolled in the study. The intervention consisted of trashing the tinnitus avatar in VR. We expected that the patients would have the subjectiv2022-01-01T00:00:00Z2022 Jul2025-04-04T07:40:26.936Z2022-08-08T22:19:28.804ZS-EPMC93006043585904410.1038/s41598-022-16764-5