{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Ramos-Rincon JM"],"pubmed_abstract":["<h4>Background</h4>Autopsies can shed light on the pathogenesis of new and emerging diseases.<h4>Aim</h4>To describe needle core necropsy findings of the lung, heart, and liver in decedents with COVID-19.<h4>Material</h4>Cross-sectional study of needle core necropsies in patients who died with virologically confirmed COVID-19. Histopathological analyses were performed, and clinical data and patient course evaluated.<h4>Results</h4>Chest core necropsies were performed in 71 decedents with a median age of 81 years (range 52-97); 47 (65.3%) were men. The median interval from symptoms onset to death was 17.5 days (range 1-84). Samples of lung (<i>n</i> = 62, 87.3%), heart (<i>n</i> = 48, 67.6%) and liver (<i>n</i> = 39, 54.9%) were obtained. Fifty-one lung samples (82.3%) were abnormal: 19 (30"],"journal":["Frontiers in medicine"],"pagination":["874307"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9301383"],"repository":["biostudies-literature"],"pubmed_title":["Pathological Findings Associated With SARS-CoV-2 on Postmortem Core Biopsies: Correlation With Clinical Presentation and Disease Course."],"pmcid":["PMC9301383"],"pubmed_authors":["Herrera-Garcia C","Merino E","Escribano I","Moreno-Perez O","Fornes-Riera FE","Concepcion-Aramendia L","Aranda I","Garcia-Sevila R","Ramos-Rincon JM","Sanchez-Martinez R","Orts-Llinares P","Alenda C","Arenas-Jimenez J","Scholz A","Munoz-Miguelsanz C","Amo-Lozano A","Portilla-Tamarit J","Pedrero-Castillo V","Ribes-Mengual I","Jaime-Sanchez FA","Marti-Pastor A","Silva-Ortega S"],"additional_accession":[]},"is_claimable":false,"name":"Pathological Findings Associated With SARS-CoV-2 on Postmortem Core Biopsies: Correlation With Clinical Presentation and Disease Course.","description":"<h4>Background</h4>Autopsies can shed light on the pathogenesis of new and emerging diseases.<h4>Aim</h4>To describe needle core necropsy findings of the lung, heart, and liver in decedents with COVID-19.<h4>Material</h4>Cross-sectional study of needle core necropsies in patients who died with virologically confirmed COVID-19. Histopathological analyses were performed, and clinical data and patient course evaluated.<h4>Results</h4>Chest core necropsies were performed in 71 decedents with a median age of 81 years (range 52-97); 47 (65.3%) were men. The median interval from symptoms onset to death was 17.5 days (range 1-84). Samples of lung (<i>n</i> = 62, 87.3%), heart (<i>n</i> = 48, 67.6%) and liver (<i>n</i> = 39, 54.9%) were obtained. Fifty-one lung samples (82.3%) were abnormal: 19 (30","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-25T18:09:37.153Z","creation":"2025-04-06T07:30:56.653Z"},"accession":"S-EPMC9301383","cross_references":{"pubmed":["35872778"],"doi":["10.3389/fmed.2022.874307"]}}