{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["28(8)"],"submitter":["Kohrs D"],"pubmed_abstract":["Herein, we report a modular synthesis providing access to substituted cycloparaphenylenes (CPPs) of different sizes. A key synthon introducing two geminal ester units was efficiently prepared by [2+2+2] cycloaddition. This building block can be conveniently converted to macrocyclic precursors controlling the ring size of the final CPP. Efficient reductive aromatization through single-electron transfer provided the substituted nanohoops in a straightforward manner. The tBu ester substitution pattern enables a tube-like arrangement in the solid-state governed by van der Waals interactions that exhibits one of the tightest packings of CPPs in tube direction, thus opening new avenues in the crystal design of CPPs."],"journal":["Chemistry (Weinheim an der Bergstrasse, Germany)"],"pagination":["e202104239"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9302675"],"repository":["biostudies-literature"],"pubmed_title":["A Modular Synthesis of Substituted Cycloparaphenylenes."],"pmcid":["PMC9302675"],"pubmed_authors":["Becker J","Kohrs D","Wegner HA"],"additional_accession":[]},"is_claimable":false,"name":"A Modular Synthesis of Substituted Cycloparaphenylenes.","description":"Herein, we report a modular synthesis providing access to substituted cycloparaphenylenes (CPPs) of different sizes. A key synthon introducing two geminal ester units was efficiently prepared by [2+2+2] cycloaddition. This building block can be conveniently converted to macrocyclic precursors controlling the ring size of the final CPP. Efficient reductive aromatization through single-electron transfer provided the substituted nanohoops in a straightforward manner. The tBu ester substitution pattern enables a tube-like arrangement in the solid-state governed by van der Waals interactions that exhibits one of the tightest packings of CPPs in tube direction, thus opening new avenues in the crystal design of CPPs.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Feb","modification":"2025-04-25T21:43:26.034Z","creation":"2025-02-19T03:53:03.855Z"},"accession":"S-EPMC9302675","cross_references":{"pubmed":["35001444"],"doi":["10.1002/chem.202104239"]}}