{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Nash D"],"funding":["National Institute of Allergy and Infectious Diseases","City University of New York","Eunice Kennedy Shriver National Institute of Child Health and Human Development","NICHD NIH HHS","NIAID NIH HHS"],"pagination":["e0271786"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9302833"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(7)"],"pubmed_abstract":["<h4>Objective</h4>To investigate the role of children in the home and household crowding as risk factors for severe COVID-19 disease.<h4>Methods</h4>We used interview data from 6,831 U.S. adults screened for the Communities, Households and SARS/CoV-2 Epidemiology (CHASING) COVID Cohort Study in April 2020.<h4>Results</h4>In logistic regression models, the adjusted odds ratio [aOR] of hospitalization due to COVID-19 for having (versus not having) children in the home was 10.5 (95% CI:5.7-19.1) among study participants living in multi-unit dwellings and 2.2 (95% CI:1.2-6.5) among those living in single unit dwellings. Among participants living in multi-unit dwellings, the aOR for COVID-19 hospitalization among participants with more than 4 persons in their household (versus 1 person) was 2.5 (95% CI:1.0-6.1), and 0.8 (95% CI:0.15-4.1) among those living in single unit dwellings.<h4>Conclusion</h4>Early in the US SARS-CoV-2 pandemic, certain household exposures likely increased the risk of both SARS-CoV-2 acquisition and the risk of severe COVID-19 disease."],"journal":["PloS one"],"pubmed_title":["Household factors and the risk of severe COVID-like illness early in the U.S. pandemic."],"pmcid":["PMC9302833"],"funding_grant_id":["P2C HD050924","COVID-19 Grant Program of the CUNY Graduate School of Public Health and Health Policy","Institute for Implementation Science in Population Health","3UH3AI133675-04S1","UH3 AI133675"],"pubmed_authors":["Rane M","Zimba R","Parcesepe A","Mirzayi C","Berry A","Qasmieh S","Waldron L","Nash D","You W","Kulkarni SG","Westmoreland D","Maroko AR","CHASING COVID Cohort Study Team","Kochhar S","Grov C","Robertson M"],"additional_accession":[]},"is_claimable":false,"name":"Household factors and the risk of severe COVID-like illness early in the U.S. pandemic.","description":"<h4>Objective</h4>To investigate the role of children in the home and household crowding as risk factors for severe COVID-19 disease.<h4>Methods</h4>We used interview data from 6,831 U.S. adults screened for the Communities, Households and SARS/CoV-2 Epidemiology (CHASING) COVID Cohort Study in April 2020.<h4>Results</h4>In logistic regression models, the adjusted odds ratio [aOR] of hospitalization due to COVID-19 for having (versus not having) children in the home was 10.5 (95% CI:5.7-19.1) among study participants living in multi-unit dwellings and 2.2 (95% CI:1.2-6.5) among those living in single unit dwellings. Among participants living in multi-unit dwellings, the aOR for COVID-19 hospitalization among participants with more than 4 persons in their household (versus 1 person) was 2.5 (95% CI:1.0-6.1), and 0.8 (95% CI:0.15-4.1) among those living in single unit dwellings.<h4>Conclusion</h4>Early in the US SARS-CoV-2 pandemic, certain household exposures likely increased the risk of both SARS-CoV-2 acquisition and the risk of severe COVID-19 disease.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-06-05T05:56:42.682Z","creation":"2022-08-08T09:56:28.237Z"},"accession":"S-EPMC9302833","cross_references":{"pubmed":["35862418"],"doi":["10.1371/journal.pone.0271786"]}}