biostudies-literatureLiu JNICHD NIH HHSNational Institute of Child Health and Human Development1370-1379https://www.ebi.ac.uk/biostudies/studies/S-EPMC9307422biostudies-literatureUnknown30(7)<h4>Objective</h4>The effectiveness of a pregnancy and postpartum behavioral lifestyle intervention on postpartum weight retention was examined.<h4>Methods</h4>Pregnant women with overweight and obesity in South Carolina were recruited into a theory-based randomized controlled trial (n = 112 intervention, n = 107 standard care), which was designed to reduce gestational weight gain and postpartum weight retention.<h4>Results</h4>Participants (44% African American, 56% White) had a mean prepregnancy BMI of 32.3 kg/m² and were at 12.6 weeks' gestation at baseline. From prepregnancy to 6 months post partum, intervention participants retained less weight than standard care women (mean difference: -3.6 kg, 95% CI: -5.5 to -1.8). The intervention effect was maintained at 12 months post partum (mean difference: -2.4 kg, 95% CI: -4.3 to -0.5). Intervention women had 2.3 times higher odds of having no weight retention at 6 months post partum versus standard care women (95% CI: 1.2 to 4.4). Intervention participants also had lower odds of retaining ≥5% of their prepregnancy weight after delivery (adjusted odds ratio: 0.3, 95% CI: 0.1 to 0.5 at 6 months; adjusted odds ratio: 0.3, 95% CI: 0.2 to 0.6 at 12 months).<h4>Conclusion</h4>This theory-based lifestyle intervention resulted in significantly less weight retention at 6 and 12 months after delivery among pregnant women with overweight and obesity.Obesity (Silver Spring, Md.)Effects of a lifestyle intervention on postpartum weight retention among women with elevated weight.PMC9307422R01 HD078407R01HD078407Liu JWilcox SHutto BWingard ETurner-McGrievy GfalseEffects of a lifestyle intervention on postpartum weight retention among women with elevated weight.<h4>Objective</h4>The effectiveness of a pregnancy and postpartum behavioral lifestyle intervention on postpartum weight retention was examined.<h4>Methods</h4>Pregnant women with overweight and obesity in South Carolina were recruited into a theory-based randomized controlled trial (n = 112 intervention, n = 107 standard care), which was designed to reduce gestational weight gain and postpartum weight retention.<h4>Results</h4>Participants (44% African American, 56% White) had a mean prepregnancy BMI of 32.3 kg/m² and were at 12.6 weeks' gestation at baseline. From prepregnancy to 6 months post partum, intervention participants retained less weight than standard care women (mean difference: -3.6 kg, 95% CI: -5.5 to -1.8). The intervention effect was maintained at 12 months post partum (mean difference: -2.4 kg, 95% CI: -4.3 to -0.5). Intervention women had 2.3 times higher odds of having no weight retention at 6 months post partum versus standard care women (95% CI: 1.2 to 4.4). Intervention participants also had lower odds of retaining ≥5% of their prepregnancy weight after delivery (adjusted odds ratio: 0.3, 95% CI: 0.1 to 0.5 at 6 months; adjusted odds ratio: 0.3, 95% CI: 0.2 to 0.6 at 12 months).<h4>Conclusion</h4>This theory-based lifestyle intervention resulted in significantly less weight retention at 6 and 12 months after delivery among pregnant women with overweight and obesity.2022-01-01T00:00:00Z2022 Jul2026-05-09T23:42:42.358Z2025-04-04T22:12:55.465ZS-EPMC93074223572281610.1002/oby.23449