{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Negretti GS"],"funding":["Medical Research Council","RCUK | Medical Research Council"],"pagination":["1669-1674"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9307816"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["36(8)"],"pubmed_abstract":["<h4>Objectives</h4>To determine survival outcomes following enucleation for uveal melanoma. To compare these outcomes with the 8th edition AJCC classification and determine the influence of cytogenetics, using Fluorescent in situ Hybridisation (FISH), on survival. To determine whether failure to gain sufficient sample for cytogenetics using Fine Needle Aspiration Biopsy (FNAB) correlates with survival.<h4>Subjects/methods</h4>All patients undergoing primary enucleation for uveal melanoma at Moorfields Eye Hospital between 2012 and 2015 were included. Clinical, pathological, cytological and survival data were analysed for all patients.<h4>Results</h4>In total, 155 subjects were included. Mean age at enucleation was 65.9 years (SD 14.13). 88 (56.8%) patients died at a mean of three (SD 1.9) "],"journal":["Eye (London, England)"],"pubmed_title":["Survival analysis following enucleation for uveal melanoma."],"pmcid":["PMC9307816"],"funding_grant_id":["MR/P027881/1","MR/P027661/1"],"pubmed_authors":["Gallo B","Arora AK","Negretti GS","Damato B","Gurudas S","Sivaprasad S","Sagoo MS"],"additional_accession":[]},"is_claimable":false,"name":"Survival analysis following enucleation for uveal melanoma.","description":"<h4>Objectives</h4>To determine survival outcomes following enucleation for uveal melanoma. To compare these outcomes with the 8th edition AJCC classification and determine the influence of cytogenetics, using Fluorescent in situ Hybridisation (FISH), on survival. To determine whether failure to gain sufficient sample for cytogenetics using Fine Needle Aspiration Biopsy (FNAB) correlates with survival.<h4>Subjects/methods</h4>All patients undergoing primary enucleation for uveal melanoma at Moorfields Eye Hospital between 2012 and 2015 were included. Clinical, pathological, cytological and survival data were analysed for all patients.<h4>Results</h4>In total, 155 subjects were included. Mean age at enucleation was 65.9 years (SD 14.13). 88 (56.8%) patients died at a mean of three (SD 1.9) ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-04T20:07:46.263Z","creation":"2025-04-04T20:07:46.263Z"},"accession":"S-EPMC9307816","cross_references":{"pubmed":["34341485"],"doi":["10.1038/s41433-021-01710-y"]}}