{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(7)"],"submitter":["Perik-Zavodskii R"],"pubmed_abstract":["Autoimmune regulator (AIRE) is a multifunctional protein that is capable of inducing tissue-specific antigens' (TSAs) gene expression, a key event in the induction of self-tolerance, that is usually expressed and functions in the thymus. However, its expression has been detected outside the thymus and cells expressing the gene have been named extra-thymic <i>AIRE</i> expressing cells (eTACs). Here, we discuss the finding of <i>AIRE</i> and TSAs gene expression in CD71+ cells from human fetal liver parenchyma, which are mostly represented by CD71+ erythroid cells."],"journal":["Genes"],"pagination":["1278"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9317677"],"repository":["biostudies-literature"],"pubmed_title":["Human Fetal Liver Parenchyma CD71+ Cells Have AIRE and Tissue-Specific Antigen Gene Expression."],"pmcid":["PMC9317677"],"pubmed_authors":["Perik-Zavodskii R","Zaitsev K","Alrhmoun S","Volynets M","Shevchenko Y","Sennikov S","Perik-Zavodskaya O"],"additional_accession":[]},"is_claimable":false,"name":"Human Fetal Liver Parenchyma CD71+ Cells Have AIRE and Tissue-Specific Antigen Gene Expression.","description":"Autoimmune regulator (AIRE) is a multifunctional protein that is capable of inducing tissue-specific antigens' (TSAs) gene expression, a key event in the induction of self-tolerance, that is usually expressed and functions in the thymus. However, its expression has been detected outside the thymus and cells expressing the gene have been named extra-thymic <i>AIRE</i> expressing cells (eTACs). Here, we discuss the finding of <i>AIRE</i> and TSAs gene expression in CD71+ cells from human fetal liver parenchyma, which are mostly represented by CD71+ erythroid cells.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jul","modification":"2025-04-22T09:51:55.373Z","creation":"2025-04-05T23:15:27.321Z"},"accession":"S-EPMC9317677","cross_references":{"pubmed":["35886060"],"doi":["10.3390/genes13071278"]}}