{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Deoni SCL"],"funding":["Medical Research Council Canada","NIDA NIH HHS","Medical Research Council","National Institutes of Health","Bill and Melinda Gates Foundation","Wellcome Trust","NIH HHS"],"pagination":["1273-1281"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9322579"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["88(3)"],"pubmed_abstract":["<h4>Purpose</h4>Low magnetic field systems provide an important opportunity to expand MRI to new and diverse clinical and research study populations. However, a fundamental limitation of low field strength systems is the reduced SNR compared to 1.5 or 3T, necessitating compromises in spatial resolution and imaging time. Most often, images are acquired with anisotropic voxels with low through-plane resolution, which provide acceptable image quality with reasonable scan times, but can impair visualization of subtle pathology.<h4>Methods</h4>Here, we describe a super-resolution approach to reconstruct high-resolution isotropic T<sub>2</sub> -weighted images from a series of low-resolution anisotropic images acquired in orthogonal orientations. Furthermore, acquiring each image with an increme"],"journal":["Magnetic resonance in medicine"],"pubmed_title":["Simultaneous high-resolution T<sub>2</sub> -weighted imaging and quantitative T<sub>2</sub> mapping at low magnetic field strengths using a multiple TE and multi-orientation acquisition approach."],"pmcid":["PMC9322579"],"funding_grant_id":["INV‐005798","206675/Z/17/Z","R34 DA050284","UG3 OD023313","MR/N026063/1","R34‐DA050284","INV‐005774"],"pubmed_authors":["Deoni SCL","Williams SCR","Huentelman M","O'Muircheartaigh J","Ljungberg E"],"additional_accession":[]},"is_claimable":false,"name":"Simultaneous high-resolution T<sub>2</sub> -weighted imaging and quantitative T<sub>2</sub> mapping at low magnetic field strengths using a multiple TE and multi-orientation acquisition approach.","description":"<h4>Purpose</h4>Low magnetic field systems provide an important opportunity to expand MRI to new and diverse clinical and research study populations. However, a fundamental limitation of low field strength systems is the reduced SNR compared to 1.5 or 3T, necessitating compromises in spatial resolution and imaging time. Most often, images are acquired with anisotropic voxels with low through-plane resolution, which provide acceptable image quality with reasonable scan times, but can impair visualization of subtle pathology.<h4>Methods</h4>Here, we describe a super-resolution approach to reconstruct high-resolution isotropic T<sub>2</sub> -weighted images from a series of low-resolution anisotropic images acquired in orthogonal orientations. Furthermore, acquiring each image with an increme","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-27T03:20:22.349Z","creation":"2025-04-06T18:49:19.134Z"},"accession":"S-EPMC9322579","cross_references":{"pubmed":["35553454"],"doi":["10.1002/mrm.29273"]}}