{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["59(6)"],"submitter":["van Limburg Stirum EVJ"],"pubmed_abstract":["Objective
To evaluate the effect of cervical pessary, as a strategy to prevent preterm birth (PTB), on the outcome of subsequent pregnancy and maternal quality of life 4 years after the index twin pregnancy.Methods
Between 2009 and 2012, the ProTWIN trial randomized women with a multiple pregnancy to pessary use vs standard care for the prevention of PTB. The trial showed no benefit in unselected women with a twin pregnancy, but showed a 60% reduction in poor perinatal outcomes in favor of the pessary group in the subgroup of women with a mid-trimester short cervix (cervical length < 38 mm). All women were invited to participate in a follow-up study 4 years after their participation in the ProTWIN trial. In this follow-up study, maternal quality of life was assessed using t"],"journal":["Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology"],"pagination":["771-777"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9328140"],"repository":["biostudies-literature"],"pubmed_title":["Consequences of cervical pessary for subsequent pregnancy: follow-up of randomized clinical trial (ProTWIN)."],"pmcid":["PMC9328140"],"pubmed_authors":["van 't Hooft J","Oudijk MA","Mol BWJ","van Limburg Stirum EVJ","Simons NE","de Boer MA","Zegveld SJ","Pajkrt E"],"additional_accession":[]},"is_claimable":false,"name":"Consequences of cervical pessary for subsequent pregnancy: follow-up of randomized clinical trial (ProTWIN).","description":"Objective
To evaluate the effect of cervical pessary, as a strategy to prevent preterm birth (PTB), on the outcome of subsequent pregnancy and maternal quality of life 4 years after the index twin pregnancy.Methods
Between 2009 and 2012, the ProTWIN trial randomized women with a multiple pregnancy to pessary use vs standard care for the prevention of PTB. The trial showed no benefit in unselected women with a twin pregnancy, but showed a 60% reduction in poor perinatal outcomes in favor of the pessary group in the subgroup of women with a mid-trimester short cervix (cervical length < 38 mm). All women were invited to participate in a follow-up study 4 years after their participation in the ProTWIN trial. In this follow-up study, maternal quality of life was assessed using t","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jun","modification":"2025-04-18T18:05:50.969Z","creation":"2025-04-07T05:43:20.271Z"},"accession":"S-EPMC9328140","cross_references":{"pubmed":["34826166"],"doi":["10.1002/uog.24821"]}}