{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Huang W"],"funding":["NICHD NIH HHS","NIEHS NIH HHS"],"pagination":["1435-1445"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9329205"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["46(8)"],"pubmed_abstract":["Background/objectives
Low-level, in-utero exposure to toxic metals such as lead (Pb) and mercury (Hg) is widespread in the US and worldwide; and, individually, was found to be obesogenic in children. To address the literature gaps on the health effects of co-exposure to low-level toxic metals and the lack of intervention strategy, we aimed to investigate the association between in-utero co-exposure to Hg, Pb, cadmium (Cd) and childhood overweight or obesity (OWO) and whether adequate maternal micronutrients (selenium (Se) and folate) can be protective.Subjects/methods
This study included 1442 mother-child pairs from the Boston Birth Cohort, a predominantly urban, low-income, Black, and Hispanic population, who were enrolled at birth and followed prospectively up to age 15 y"],"journal":["International journal of obesity (2005)"],"pubmed_title":["In-utero co-exposure to toxic metals and micronutrients on childhood risk of overweight or obesity: new insight on micronutrients counteracting toxic metals."],"pmcid":["PMC9329205"],"funding_grant_id":["R03 ES029594","R01 ES031272","R21 ES011666","R01 HD086013","R01 HD041702","R01 ES031521","R21 HD066471","R01 HD098232"],"pubmed_authors":["Haltmeier D","Xu R","Igusa T","Wang G","Hou W","Mukherjee J","Steffens A","Hong X","Huang W","Buckley JP","Bind E","Ji Y","Wang X","Tina Fan Z"],"additional_accession":[]},"is_claimable":false,"name":"In-utero co-exposure to toxic metals and micronutrients on childhood risk of overweight or obesity: new insight on micronutrients counteracting toxic metals.","description":"Background/objectives
Low-level, in-utero exposure to toxic metals such as lead (Pb) and mercury (Hg) is widespread in the US and worldwide; and, individually, was found to be obesogenic in children. To address the literature gaps on the health effects of co-exposure to low-level toxic metals and the lack of intervention strategy, we aimed to investigate the association between in-utero co-exposure to Hg, Pb, cadmium (Cd) and childhood overweight or obesity (OWO) and whether adequate maternal micronutrients (selenium (Se) and folate) can be protective.Subjects/methods
This study included 1442 mother-child pairs from the Boston Birth Cohort, a predominantly urban, low-income, Black, and Hispanic population, who were enrolled at birth and followed prospectively up to age 15 y","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2026-05-09T13:39:09.999Z","creation":"2024-11-09T22:27:18.85Z"},"accession":"S-EPMC9329205","cross_references":{"pubmed":["35589962"],"doi":["10.1038/s41366-022-01127-x"]}}