{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Randhawa AS"],"funding":["NINDS NIH HHS"],"pagination":["2426-2434"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9329219"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["53(8)"],"pubmed_abstract":["<h4>Background</h4>To emphasize treatment speed for time-sensitive conditions, emergency medicine has developed not only the concept of the golden hour, but also the platinum half-hour. Patients with acute stroke treated within the first half-hour of onset have not been previously characterized.<h4>Methods</h4>In this cohort study, we analyzed patients enrolled in the FAST-MAG (Field Administration of Stroke Therapy-Magnesium) trial, testing paramedic prehospital start of neuroprotective agent ≤2 hours of onset. The features of all acute cerebral ischemia, and intracranial hemorrhage patients with treatment starting at ≤30 m of last known well were compared with later-treated patients.<h4>Results</h4>Among 1680 patients, 203 (12.1%) received study agents within 30 minutes of last known wel"],"journal":["Stroke"],"pubmed_title":["Beyond the Golden Hour: Treating Acute Stroke in the Platinum 30 Minutes."],"pmcid":["PMC9329219"],"funding_grant_id":["U01 NS044364"],"pubmed_authors":["Valdes-Sueiras M","Restrepo-Jimenez L","Conwit R","Hamilton S","Villablanca P","Pariona-Vargas F","Gornbein J","Sharma L","Randhawa AS","Saver JL","Sanossian N","Liebeskind DS","Kim-Tenser M","Starkman S","Avila G","Stratton S"],"additional_accession":[]},"is_claimable":false,"name":"Beyond the Golden Hour: Treating Acute Stroke in the Platinum 30 Minutes.","description":"<h4>Background</h4>To emphasize treatment speed for time-sensitive conditions, emergency medicine has developed not only the concept of the golden hour, but also the platinum half-hour. Patients with acute stroke treated within the first half-hour of onset have not been previously characterized.<h4>Methods</h4>In this cohort study, we analyzed patients enrolled in the FAST-MAG (Field Administration of Stroke Therapy-Magnesium) trial, testing paramedic prehospital start of neuroprotective agent ≤2 hours of onset. The features of all acute cerebral ischemia, and intracranial hemorrhage patients with treatment starting at ≤30 m of last known well were compared with later-treated patients.<h4>Results</h4>Among 1680 patients, 203 (12.1%) received study agents within 30 minutes of last known wel","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-04T20:06:55.677Z","creation":"2025-04-04T20:06:55.677Z"},"accession":"S-EPMC9329219","cross_references":{"pubmed":["35545939"],"doi":["10.1161/STROKEAHA.121.036993","10.1161/strokeaha.121.036993"]}}