{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(1)"],"submitter":["Galasso L"],"pubmed_abstract":["The aim of the present study is to explore the potential association between sleep quality and physical activity (PA) in women carriers of BRCA1/2 mutations. 63 women completed the Pittsburgh Sleep Quality Index (PSQI) and Godin Shepard Leisure-Time Physical Activity Questionnaire (GSL-TPAQ) and were included in the present cross-sectional analysis. Globally, women showed a PSQI score of 7.0 ± 3.6 and a GSL-TPAQ score of 22.8 ± 18.3. Good sleepers (PSQI score ≤ 5) showed significantly higher PA levels compared to bad sleepers (PSQI score > 5). Women in the higher tertile of GSL-TPAQ total score (≥ 27 METs/week) have a prevalence ratio (PR) of being a good sleeper of 2.85 (1.25-6.52, 95% confidence intervals) compared to women in the lower tertile (≤ 11 METs/week). These results were consistent in BRCA1 and BRCA2 women. Considering each single question of PA intensity, the PR of being a good sleeper by unit of increase of MET/week was higher and significant in women engaged in strenuous and moderate intensity PA. These results suggests a direct association between PA and sleep quality in women carriers of BRCA mutations."],"journal":["Scientific reports"],"pagination":["12873"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9329454"],"repository":["biostudies-literature"],"pubmed_title":["Physical activity and sleep behaviour in women carrying BRCA1/2 mutations."],"pmcid":["PMC9329454"],"pubmed_authors":["Roveda E","Montaruli A","Castelli L","Galasso L","Bruno E","Baldassari I","Pasanisi P","Esposito F","Oliverio A","Mule A"],"additional_accession":[]},"is_claimable":false,"name":"Physical activity and sleep behaviour in women carrying BRCA1/2 mutations.","description":"The aim of the present study is to explore the potential association between sleep quality and physical activity (PA) in women carriers of BRCA1/2 mutations. 63 women completed the Pittsburgh Sleep Quality Index (PSQI) and Godin Shepard Leisure-Time Physical Activity Questionnaire (GSL-TPAQ) and were included in the present cross-sectional analysis. Globally, women showed a PSQI score of 7.0 ± 3.6 and a GSL-TPAQ score of 22.8 ± 18.3. Good sleepers (PSQI score ≤ 5) showed significantly higher PA levels compared to bad sleepers (PSQI score > 5). Women in the higher tertile of GSL-TPAQ total score (≥ 27 METs/week) have a prevalence ratio (PR) of being a good sleeper of 2.85 (1.25-6.52, 95% confidence intervals) compared to women in the lower tertile (≤ 11 METs/week). These results were consistent in BRCA1 and BRCA2 women. Considering each single question of PA intensity, the PR of being a good sleeper by unit of increase of MET/week was higher and significant in women engaged in strenuous and moderate intensity PA. These results suggests a direct association between PA and sleep quality in women carriers of BRCA mutations.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jul","modification":"2024-11-20T21:06:04.719Z","creation":"2024-11-20T21:06:04.719Z"},"accession":"S-EPMC9329454","cross_references":{"pubmed":["35896655"],"doi":["10.1038/s41598-022-16687-1"]}}