biostudies-literatureChen RKey-Area Research and Development Program of Guangdong ProvinceGuangzhou Science and Technology Plan Projects"14th Five-Year Plan" team-building projects of Guangdong Academy of Agricultural SciencesSpecial fund for scientific innovation strategy-construction of high level Academy of Agriculture ScienceGuangdong Basic and Applied Basic Research FoundationQingyuan Science and Technology Programthe Innovation Fund projects of Guangdong Key Laboratory of Tea Plant Resources Innovation and UtilizationInnovation Fund projects of Guangdong Academy of Agricultural Sciences3037https://www.ebi.ac.uk/biostudies/studies/S-EPMC9332116biostudies-literatureUnknown14(15)Liver injury is a significant public health issue nowadays. Shibi tea is a non-<i>Camellia</i> tea prepared from the dried leaves of <i>Adinandra nitida</i>, one of the plants with the greatest flavonoid concentration, with Camellianin A (CA) being the major flavonoid. Shibi tea is extensively used in food and medicine and has been found to provide a variety of health advantages. The benefits of Shibi tea and CA in preventing liver injury have not yet been investigated. The aim of this study was to investigate the hepatoprotective effects of extract of Shibi tea (EST) and CA in mice with carbon tetrachloride (CCl₄)-induced acute liver injury. Two different concentrations of EST and CA were given to model mice by gavage for 3 days. Treatment with two concentrations of EST and CA NutrientsShibi Tea (<i>Adinandra nitida</i>) and Camellianin A Alleviate CCl₄-Induced Liver Injury in C57BL-6J Mice by Attenuation of Oxidative Stress, Inflammation, and Apoptosis.PMC93321162020B0202080003202126TD2020A1515011266, 2021A1515010958202102020047, 202002030202DZXQY021202115, 2020352021CX02R2019PY-JX004Sun LLai XTang LYuan EZhu JZhang ZLian YSun SWen SLi QXuan JChen RfalseShibi Tea (<i>Adinandra nitida</i>) and Camellianin A Alleviate CCl₄-Induced Liver Injury in C57BL-6J Mice by Attenuation of Oxidative Stress, Inflammation, and Apoptosis.Liver injury is a significant public health issue nowadays. Shibi tea is a non-<i>Camellia</i> tea prepared from the dried leaves of <i>Adinandra nitida</i>, one of the plants with the greatest flavonoid concentration, with Camellianin A (CA) being the major flavonoid. Shibi tea is extensively used in food and medicine and has been found to provide a variety of health advantages. The benefits of Shibi tea and CA in preventing liver injury have not yet been investigated. The aim of this study was to investigate the hepatoprotective effects of extract of Shibi tea (EST) and CA in mice with carbon tetrachloride (CCl₄)-induced acute liver injury. Two different concentrations of EST and CA were given to model mice by gavage for 3 days. Treatment with two concentrations of EST and CA 2022-01-01T00:00:00Z2022 Jul2025-04-19T17:48:22.016Z2022-08-06T14:52:53.962ZS-EPMC93321163589389110.3390/nu14153037