biostudies-literatureNguyen TKExploratory Research for Advanced TechnologyGriffith UniversitySchool of Mechanical and Manufacturing Engineering, The University of New South WalesAustralian Research Council10890-10903https://www.ebi.ac.uk/biostudies/studies/S-EPMC9332346biostudies-literatureUnknown16(7)The integration of micro- and nanoelectronics into or onto biomedical devices can facilitate advanced diagnostics and treatments of digestive disorders, cardiovascular diseases, and cancers. Recent developments in gastrointestinal endoscopy and balloon catheter technologies introduce promising paths for minimally invasive surgeries to treat these diseases. However, current therapeutic endoscopy systems fail to meet requirements in multifunctionality, biocompatibility, and safety, particularly when integrated with bioelectronic devices. Here, we report materials, device designs, and assembly schemes for transparent and stable cubic silicon carbide (3C-SiC)-based bioelectronic systems that facilitate tissue ablation, with the capability for integration onto the tips of endoscopes. The excellACS nanoIntegrated, Transparent Silicon Carbide Electronics and Sensors for Radio Frequency Biomedical Therapy.PMC9332346DE200100238JPMJER2003Dau VBarton MTruong TAHan MChen LNguyen NTAshok AVu HPhan HPPark YGuzman PDinh TNguyen TKYamauchi YLeitch MYadav SHaasmann DDo TNRogers JAfalseIntegrated, Transparent Silicon Carbide Electronics and Sensors for Radio Frequency Biomedical Therapy.The integration of micro- and nanoelectronics into or onto biomedical devices can facilitate advanced diagnostics and treatments of digestive disorders, cardiovascular diseases, and cancers. Recent developments in gastrointestinal endoscopy and balloon catheter technologies introduce promising paths for minimally invasive surgeries to treat these diseases. However, current therapeutic endoscopy systems fail to meet requirements in multifunctionality, biocompatibility, and safety, particularly when integrated with bioelectronic devices. Here, we report materials, device designs, and assembly schemes for transparent and stable cubic silicon carbide (3C-SiC)-based bioelectronic systems that facilitate tissue ablation, with the capability for integration onto the tips of endoscopes. The excell2022-01-01T00:00:00Z2022 Jul2025-04-20T03:43:27.295Z2025-04-20T03:43:27.295ZS-EPMC93323463581645010.1021/acsnano.2c03188