{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Lacerda S"],"funding":["H2020 Marie Sklodowska-Curie Actions","Wellcome Trust"],"pubmed_abstract":["Porous materials, such as zeolites, have great potential for biomedical applications, thanks to their ability to accommodate positively charged metal-ions and their facile surface functionalization. Although the latter aspect is important to endow the nanoparticles with chemical/colloidal stability and desired biological properties, the possibility for simple ion-exchange enables easy switching between imaging modalities and/or combination with therapy, depending on the envisioned application. In this study, the nanozeolite Linde type L (LTL) with already confirmed magnetic resonance imaging properties, generated by the paramagnetic gadolinium (Gd<sup>III</sup>) in the inner cavities, was successfully radiolabeled with a positron emission tomography (PET)-tracer zirconium-89 (<sup>89</sup>"],"journal":["ACS applied materials & interfaces"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9335405"],"repository":["biostudies-literature"],"pubmed_title":["On the Versatility of Nanozeolite Linde Type L for Biomedical Applications: Zirconium-89 Radiolabeling and In Vivo Positron Emission Tomography Study."],"pmcid":["PMC9335405"],"funding_grant_id":["084052/Z/07/Z","088641/Z/09/Z","665790"],"pubmed_authors":["Zhang W","Lacerda S","T M de Rosales R","Da Silva I","Sobilo J","Lerondel S","Djanashvili K","Toth E"],"additional_accession":[]},"is_claimable":false,"name":"On the Versatility of Nanozeolite Linde Type L for Biomedical Applications: Zirconium-89 Radiolabeling and In Vivo Positron Emission Tomography Study.","description":"Porous materials, such as zeolites, have great potential for biomedical applications, thanks to their ability to accommodate positively charged metal-ions and their facile surface functionalization. Although the latter aspect is important to endow the nanoparticles with chemical/colloidal stability and desired biological properties, the possibility for simple ion-exchange enables easy switching between imaging modalities and/or combination with therapy, depending on the envisioned application. In this study, the nanozeolite Linde type L (LTL) with already confirmed magnetic resonance imaging properties, generated by the paramagnetic gadolinium (Gd<sup>III</sup>) in the inner cavities, was successfully radiolabeled with a positron emission tomography (PET)-tracer zirconium-89 (<sup>89</sup>","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jul","modification":"2025-04-27T01:11:34.694Z","creation":"2025-04-06T18:07:39.123Z"},"accession":"S-EPMC9335405","cross_references":{"pubmed":["35830285"],"doi":["10.1021/acsami.2c03841"]}}