{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Baker AJ"],"funding":["Division of Civil, Mechanical and Manufacturing Innovation"],"pagination":["5954-5960"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9335865"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["22(14)"],"pubmed_abstract":["The adhesion between nanoscale components has been shown to increase with applied load, contradicting well-established mechanics models. Here, we use <i>in situ</i> transmission electron microscopy and atomistic simulations to reveal the underlying mechanism for this increase as a change in the mode of separation. Analyzing 135 nanoscale adhesion tests on technologically relevant materials of anatase TiO<sub>2</sub>, silicon, and diamond, we demonstrate a transition from fracture-controlled to strength-controlled separation. When fracture models are incorrectly applied, they yield a 7-fold increase in <i>apparent</i> work of adhesion; however, we show that the <i>true</i> work of adhesion is unchanged with loading. Instead, the nanoscale adhesion is governed by the product of adhesive stre"],"journal":["Nano letters"],"pubmed_title":["Origin of Pressure-Dependent Adhesion in Nanoscale Contacts."],"pmcid":["PMC9335865"],"funding_grant_id":["1844739","1537613","1536800"],"pubmed_authors":["Baker AJ","Martini A","Jacobs TDB","Vishnubhotla SB","Chen R"],"additional_accession":[]},"is_claimable":false,"name":"Origin of Pressure-Dependent Adhesion in Nanoscale Contacts.","description":"The adhesion between nanoscale components has been shown to increase with applied load, contradicting well-established mechanics models. Here, we use <i>in situ</i> transmission electron microscopy and atomistic simulations to reveal the underlying mechanism for this increase as a change in the mode of separation. Analyzing 135 nanoscale adhesion tests on technologically relevant materials of anatase TiO<sub>2</sub>, silicon, and diamond, we demonstrate a transition from fracture-controlled to strength-controlled separation. When fracture models are incorrectly applied, they yield a 7-fold increase in <i>apparent</i> work of adhesion; however, we show that the <i>true</i> work of adhesion is unchanged with loading. Instead, the nanoscale adhesion is governed by the product of adhesive stre","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jul","modification":"2026-03-31T11:21:02.881Z","creation":"2025-04-06T18:09:03.145Z"},"accession":"S-EPMC9335865","cross_references":{"pubmed":["35793499"],"doi":["10.1021/acs.nanolett.2c02016"]}}