biostudies-literatureUnknown6(6)Carey C<h4>Background</h4>Takotsubo cardiomyopathy (TC) is a disease that causes transient left ventricular (LV) dysfunction in multiple vascular territories in the absence of coronary artery disease. Takotsubo cardiomyopathy is typically associated with dilation and dyskinesia of the apical and mid-LV segments induced by acute emotional and/or physical stress. Here, we present a case of recurrent TC including one episode of inverted TC, which is a rare form where dyskinesia occurs in the basal segments with sparing of the apical segments.<h4>Case summary</h4>A 53-year-old female patient with a background history of chronic stress and anxiety was admitted with three episodes of recurrent TC over 4 years. The first episode in 2017 was triggered by an acute stressful event, but no major triggers weEuropean heart journal. Case reportsytac207https://www.ebi.ac.uk/biostudies/studies/S-EPMC9336569biostudies-literatureA case report of recurrent takotsubo cardiomyopathy including the rare 'inverted' form.PMC9336569Macnab ANucifora GCarey CfalseA case report of recurrent takotsubo cardiomyopathy including the rare 'inverted' form.<h4>Background</h4>Takotsubo cardiomyopathy (TC) is a disease that causes transient left ventricular (LV) dysfunction in multiple vascular territories in the absence of coronary artery disease. Takotsubo cardiomyopathy is typically associated with dilation and dyskinesia of the apical and mid-LV segments induced by acute emotional and/or physical stress. Here, we present a case of recurrent TC including one episode of inverted TC, which is a rare form where dyskinesia occurs in the basal segments with sparing of the apical segments.<h4>Case summary</h4>A 53-year-old female patient with a background history of chronic stress and anxiety was admitted with three episodes of recurrent TC over 4 years. The first episode in 2017 was triggered by an acute stressful event, but no major triggers we2022-01-01T00:00:00Z2022 Jun2025-04-18T18:06:57.361Z2025-04-07T05:46:17.337ZS-EPMC93365693590950510.1093/ehjcr/ytac207