biostudies-literatureWang YPostgraduate Research & Practice Innovation Program of Jiangsu ProvinceFundamental Research Funds for the Central UniversitiesNational Natural Science Foundation of ChinaNational Key Research and Development Program of China4419https://www.ebi.ac.uk/biostudies/studies/S-EPMC9338087biostudies-literatureUnknown13(1)Tooth whitening has recently become one of the most popular aesthetic dentistry procedures. Beyond classic hydrogen peroxide-based whitening agents, photo-catalysts and piezo-catalysts have been demonstrated for non-destructive on-demand tooth whitening. However, their usage has been challenged due to the relatively limited physical stimuli of light irradiation and ultrasonic mechanical vibration. To address this challenge, we report here a non-destructive and convenient tooth whitening strategy based on the pyro-catalysis effect, realized via ubiquitous oral motion-induced temperature fluctuations. Degradation of organic dyes via pyro-catalysis is performed under cooling/heating cycling to simulate natural temperature fluctuations associated with intake and speech. Teeth stained by habituNature communicationsPyro-catalysis for tooth whitening via oral temperature fluctuation.PMC9338087819915058202201652072178U21A206651790492Li XLiu ZLi DWang SZhang XWang YBai YMeng YYuan GDeng XfalsePyro-catalysis for tooth whitening via oral temperature fluctuation.Tooth whitening has recently become one of the most popular aesthetic dentistry procedures. Beyond classic hydrogen peroxide-based whitening agents, photo-catalysts and piezo-catalysts have been demonstrated for non-destructive on-demand tooth whitening. However, their usage has been challenged due to the relatively limited physical stimuli of light irradiation and ultrasonic mechanical vibration. To address this challenge, we report here a non-destructive and convenient tooth whitening strategy based on the pyro-catalysis effect, realized via ubiquitous oral motion-induced temperature fluctuations. Degradation of organic dyes via pyro-catalysis is performed under cooling/heating cycling to simulate natural temperature fluctuations associated with intake and speech. Teeth stained by habitu2022-01-01T00:00:00Z2022 Jul2025-04-04T19:27:29.137Z2025-04-04T19:27:29.137ZS-EPMC93380873590622110.1038/s41467-022-32132-3