{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(1)"],"submitter":["Jang YC"],"pubmed_abstract":["Hormone replacement therapy (HRT) is widely used to relieve menopausal symptoms; however, it remains unclear whether the use of HRT was associated with gastric cancer. We conducted a systematic review and meta-analysis to synthesize available evidence. This study followed the PRISMA guideline to report meta-analysis. PubMed, Embase, and Cochrane library were searched from conception through 23 February 2022. Eligible studies reporting risk of gastric cancer after HRT were screened and accessed by two independent reviewers. Random-effects meta-analysis was used to calculate pooled risk estimate as relative risk (RR, 95% CI). Pre-established review protocol was registered in PROSPERO (CRD42021281260). Among the 1095 articles identified, we included 11 studies with 1,919,089 women in this met"],"journal":["Scientific reports"],"pagination":["12997"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9338312"],"repository":["biostudies-literature"],"pubmed_title":["Association of hormone replacement therapy with risk of gastric cancer: a systematic review and meta-analysis."],"pmcid":["PMC9338312"],"pubmed_authors":["Leung CY","Huang HL","Jang YC"],"additional_accession":[]},"is_claimable":false,"name":"Association of hormone replacement therapy with risk of gastric cancer: a systematic review and meta-analysis.","description":"Hormone replacement therapy (HRT) is widely used to relieve menopausal symptoms; however, it remains unclear whether the use of HRT was associated with gastric cancer. We conducted a systematic review and meta-analysis to synthesize available evidence. This study followed the PRISMA guideline to report meta-analysis. PubMed, Embase, and Cochrane library were searched from conception through 23 February 2022. Eligible studies reporting risk of gastric cancer after HRT were screened and accessed by two independent reviewers. Random-effects meta-analysis was used to calculate pooled risk estimate as relative risk (RR, 95% CI). Pre-established review protocol was registered in PROSPERO (CRD42021281260). Among the 1095 articles identified, we included 11 studies with 1,919,089 women in this met","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jul","modification":"2025-04-22T03:29:15.141Z","creation":"2025-04-05T20:42:14.147Z"},"accession":"S-EPMC9338312","cross_references":{"pubmed":["35906381"],"doi":["10.1038/s41598-022-17345-2"]}}