{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Robertson JM"],"funding":["FIC NIH HHS","NHLBI NIH HHS","Fogarty International Center","SHARE INDIA Research Foundation"],"pagination":["314-321"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9339451"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["72(4)"],"pubmed_abstract":["<h4>Background</h4>Consanguineous marriage (CM) has been linked to spontaneous abortion (SAB), although studies have largely been cross-sectional and likely underestimated early loss. We aimed to determine the relationships between CM and SAB in a prospective pregnancy cohort study in Telangana State, India.<h4>Methods</h4>Data from 661 participants aged 15-35 years in the Longitudinal Indian Family hEalth (LIFE) study actively followed for pregnancy and pregnancy loss were analyzed. SAB was classified as early (< 8) or late (8-22) weeks gestation. We used logistic regression to model the relationships between CM, defined by first-cousin marriage, and SAB, adjusted for maternal age.<h4>Results</h4>Women in CM were at a modestly increased risk of any (OR<sub>adj</sub> 1.15, 95% CI 0.69, 1.9"],"journal":["Journal of obstetrics and gynaecology of India"],"pubmed_title":["Consanguineous Marriage and Early Pregnancy Loss in Rural to Peri-Urban India."],"pmcid":["PMC9339451"],"funding_grant_id":["D43 TW 009078","T32 HL083825","D43 TW009078"],"pubmed_authors":["Robertson JM","Basany K","Haggerty CL","Tan X","Farooq F","Tang G","Bunker CH","Reddy PS"],"additional_accession":[]},"is_claimable":false,"name":"Consanguineous Marriage and Early Pregnancy Loss in Rural to Peri-Urban India.","description":"<h4>Background</h4>Consanguineous marriage (CM) has been linked to spontaneous abortion (SAB), although studies have largely been cross-sectional and likely underestimated early loss. We aimed to determine the relationships between CM and SAB in a prospective pregnancy cohort study in Telangana State, India.<h4>Methods</h4>Data from 661 participants aged 15-35 years in the Longitudinal Indian Family hEalth (LIFE) study actively followed for pregnancy and pregnancy loss were analyzed. SAB was classified as early (< 8) or late (8-22) weeks gestation. We used logistic regression to model the relationships between CM, defined by first-cousin marriage, and SAB, adjusted for maternal age.<h4>Results</h4>Women in CM were at a modestly increased risk of any (OR<sub>adj</sub> 1.15, 95% CI 0.69, 1.9","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-04T20:07:02.618Z","creation":"2025-04-04T20:07:02.618Z"},"accession":"S-EPMC9339451","cross_references":{"pubmed":["35923508"],"doi":["10.1007/s13224-021-01498-7"]}}