biostudies-literatureUnknown50(7)Shaveisi-Zadeh F<h4>Objective</h4>COVID-19 has recently emerged as a serious threat to global health. This study examined the laboratory investigations of patients with COVID-19, with an emphasis on liver enzymes.<h4>Methods</h4>This retrospective, single-center study was performed on patients with COVID-19 who were admitted to Imam Reza Hospital, Iran from March 2020 to February 2021. Laboratory tests included a complete blood cell count, white blood cell (WBC) count, neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), lymphocyte/monocyte ratio, and levels of aspartate aminotransferase, alanine aminotransferase (ALT), and alkaline phosphatase. Patient survival was among the outcome measures investigated in association with laboratory findings.<h4>Results</h4>We enrolled 77 patients with CThe Journal of international medical research3000605221110067https://www.ebi.ac.uk/biostudies/studies/S-EPMC9340912biostudies-literatureChanges in liver enzymes and association with prognosis in patients with COVID-19: a retrospective case-control study.PMC9340912Nikkho BRostami-Far ZAzizi AShaveisi-Zadeh FTarlan MAmiri AMansouri NKhadem Erfan MBfalseChanges in liver enzymes and association with prognosis in patients with COVID-19: a retrospective case-control study.<h4>Objective</h4>COVID-19 has recently emerged as a serious threat to global health. This study examined the laboratory investigations of patients with COVID-19, with an emphasis on liver enzymes.<h4>Methods</h4>This retrospective, single-center study was performed on patients with COVID-19 who were admitted to Imam Reza Hospital, Iran from March 2020 to February 2021. Laboratory tests included a complete blood cell count, white blood cell (WBC) count, neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), lymphocyte/monocyte ratio, and levels of aspartate aminotransferase, alanine aminotransferase (ALT), and alkaline phosphatase. Patient survival was among the outcome measures investigated in association with laboratory findings.<h4>Results</h4>We enrolled 77 patients with C2022-01-01T00:00:00Z2022 Jul2025-04-22T11:33:48.877Z2025-04-05T23:58:35.025ZS-EPMC93409123590386110.1177/03000605221110067