biostudies-literatureUnknown10(9)Fan X<h4>Background and objective</h4>As the vascular theory has led many researchers to focus on vascular dysfunction in the pathogenesis of glaucoma, a better understanding of ocular microcirculation would be of great significance. The emergence of optical coherence tomography angiography (OCTA) has shed light on the various fundus microvascular changes that occur in glaucoma, thus providing ample evidence in the role of microvascular dysfunction in glaucoma. The aim of this review is to provide an overview of the retinal and choroidal microvascular alterations that occur in glaucoma and to address the role of microvascular alterations in the pathogenesis, diagnosis, prognosis, and treatment of glaucoma.<h4>Methods</h4>The literature regarding fundus microvascular alterations in glaucoma and Annals of translational medicine527https://www.ebi.ac.uk/biostudies/studies/S-EPMC9347045biostudies-literatureThe characteristics of fundus microvascular alterations in the course of glaucoma: a narrative review.PMC9347045Fan XZhai RYing YSheng QXu HSun YKong XfalseThe characteristics of fundus microvascular alterations in the course of glaucoma: a narrative review.<h4>Background and objective</h4>As the vascular theory has led many researchers to focus on vascular dysfunction in the pathogenesis of glaucoma, a better understanding of ocular microcirculation would be of great significance. The emergence of optical coherence tomography angiography (OCTA) has shed light on the various fundus microvascular changes that occur in glaucoma, thus providing ample evidence in the role of microvascular dysfunction in glaucoma. The aim of this review is to provide an overview of the retinal and choroidal microvascular alterations that occur in glaucoma and to address the role of microvascular alterations in the pathogenesis, diagnosis, prognosis, and treatment of glaucoma.<h4>Methods</h4>The literature regarding fundus microvascular alterations in glaucoma and 2022-01-01T00:00:00Z2022 May2025-06-01T00:35:14.464Z2024-11-13T05:58:42.822ZS-EPMC93470453592875210.21037/atm-21-5695