{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["127(8)"],"submitter":["Bicchetti M"],"funding":["Università degli Studi di Roma La Sapienza"],"pubmed_abstract":["<h4>Purpose</h4>To determine the clinical, pathological, and radiological features, including the Vesical Imaging-Reporting and Data System (VI-RADS) score, independently correlating with muscle-invasive bladder cancer (BCa), in a multicentric national setting.<h4>Method and materials</h4>Patients with BCa suspicion were offered magnetic resonance imaging (MRI) before trans-urethral resection of bladder tumor (TURBT). According to VI-RADS, a cutoff of ≥ 3 or ≥ 4 was assumed to define muscle-invasive bladder cancer (MIBC). Trans-urethral resection of the tumor (TURBT) and/or cystectomy reports were compared with preoperative VI-RADS scores to assess accuracy of MRI for discriminating between non-muscle-invasive versus MIBC. Performance was assessed by ROC curve analysis. Two univariable and"],"journal":["La Radiologia medica"],"pagination":["881-890"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9349064"],"repository":["biostudies-literature"],"pubmed_title":["A novel pathway to detect muscle-invasive bladder cancer based on integrated clinical features and VI-RADS score on MRI: results of a prospective multicenter study."],"pmcid":["PMC9349064"],"pubmed_authors":["Schiavina R","Panebianco V","Briganti A","Brunocilla E","De Cobelli F","Flammia S","Catalano C","Girometti R","Cardone G","Bicchetti M","Simone G","Pecoraro M","Leonardo C","Giannarini G","Gaudiano C","Del Giudice F"],"additional_accession":[]},"is_claimable":false,"name":"A novel pathway to detect muscle-invasive bladder cancer based on integrated clinical features and VI-RADS score on MRI: results of a prospective multicenter study.","description":"<h4>Purpose</h4>To determine the clinical, pathological, and radiological features, including the Vesical Imaging-Reporting and Data System (VI-RADS) score, independently correlating with muscle-invasive bladder cancer (BCa), in a multicentric national setting.<h4>Method and materials</h4>Patients with BCa suspicion were offered magnetic resonance imaging (MRI) before trans-urethral resection of bladder tumor (TURBT). According to VI-RADS, a cutoff of ≥ 3 or ≥ 4 was assumed to define muscle-invasive bladder cancer (MIBC). Trans-urethral resection of the tumor (TURBT) and/or cystectomy reports were compared with preoperative VI-RADS scores to assess accuracy of MRI for discriminating between non-muscle-invasive versus MIBC. Performance was assessed by ROC curve analysis. Two univariable and","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-04T22:36:35.864Z","creation":"2025-04-04T22:36:35.864Z"},"accession":"S-EPMC9349064","cross_references":{"pubmed":["35763251"],"doi":["10.1007/s11547-022-01513-5"]}}