{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["43(8)"],"submitter":["Boschi A"],"pubmed_abstract":["Purpose
The aim of this study is to compare the use of 5-aminolevulinic acid (5-ALA) and sodium fluorescein (SF) in IV ventricular ependymoma (IVEP) surgical resection.Methods
In this retrospective study, six patients with IVEP were enrolled. Gender ratio 2:1 male to female, with mean age 38.9 years old. A 5-ALA oral dose of 20 mg/kg and a SF intravenous dose of 2 mg/kg were administered. Telo-velar approach, operative microscope, and intraoperative monitoring were used in all the operations. We retrospectively compared the two fluorescence techniques at four steps during the surgical procedure: step 1: exposure of the tumor; step 2: dissection of the lesion from the cerebellum; step 3: assessment of the tumor borders and differentiation from normal tissue at the base of im"],"journal":["Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology"],"pagination":["5075-5082"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9349074"],"repository":["biostudies-literature"],"pubmed_title":["5-aminolevulinic acid and sodium fluorescein in IV ventricle ependymoma surgery: preliminary experience comparing the two techniques."],"pmcid":["PMC9349074"],"pubmed_authors":["Becattini E","Lastrucci G","Della Puppa A","Boschi A","Pisano A","Buccoliero A"],"additional_accession":[]},"is_claimable":false,"name":"5-aminolevulinic acid and sodium fluorescein in IV ventricle ependymoma surgery: preliminary experience comparing the two techniques.","description":"Purpose
The aim of this study is to compare the use of 5-aminolevulinic acid (5-ALA) and sodium fluorescein (SF) in IV ventricular ependymoma (IVEP) surgical resection.Methods
In this retrospective study, six patients with IVEP were enrolled. Gender ratio 2:1 male to female, with mean age 38.9 years old. A 5-ALA oral dose of 20 mg/kg and a SF intravenous dose of 2 mg/kg were administered. Telo-velar approach, operative microscope, and intraoperative monitoring were used in all the operations. We retrospectively compared the two fluorescence techniques at four steps during the surgical procedure: step 1: exposure of the tumor; step 2: dissection of the lesion from the cerebellum; step 3: assessment of the tumor borders and differentiation from normal tissue at the base of im","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-27T01:08:26.996Z","creation":"2025-04-06T18:08:23.757Z"},"accession":"S-EPMC9349074","cross_references":{"pubmed":["35334013"],"doi":["10.1007/s10072-022-06012-z"]}}