biostudies-literatureUnknownBarendse MEABrain & Behavior Research FoundationNIMH NIH HHSUniversity of TexasHellman Fellows FundInstitution of Education SciencesUniversity of Missouri Research CouncilUniversity of South-FloridaEuropean Research CouncilNational Science FoundationThe University of Texas at El PasoKlingenstein Third Generation FoundationUTEP Center for Law and Border StudiesNIDA NIH HHSJacobs FoundationStanford Center for Cognitive and Neurobiological ImagingVirginia Tech COVID-19 Rapid Response Seed FundCincinnati Children's Research FoundationUCR Center for Health Disparities ResearchRay and Dagmar Dolby Family FundAmerican Psychological FoundationBezos Family FoundationNIMHD NIH HHSNational Institute of Mental HealthNational Institute on Drug AbuseStanford Maternal and Child Health Research InstituteThis study aimed to examine changes in depression and anxiety symptoms from before to during the first 6 months of the COVID-19 pandemic in a sample of 1,339 adolescents (9-18 years old, 59% female) from three countries. We also examined if age, race/ethnicity, disease burden, or strictness of government restrictions moderated change in symptoms. Data from 12 longitudinal studies (10 U.S., 1 Netherlands, 1 Peru) were combined. Linear mixed effect models showed that depression, but not anxiety, symptoms increased significantly (median increase = 28%). The most negative mental health impacts were reported by multiracial adolescents and those under 'lockdown' restrictions. Policy makers need to consider these impacts by investing in ways to support adolescents' mental health during the pandemJournal of research on adolescence : the official journal of the Society for Research on Adolescencehttps://www.ebi.ac.uk/biostudies/studies/S-EPMC9349954biostudies-literatureLongitudinal Change in Adolescent Depression and Anxiety Symptoms from before to during the COVID-19 Pandemic.PMC9349954NSF-2018-1826773SES 1459719K01MH117442R01DA039923R56 MH1117002018-1288-13U54 MD013368R37MH10149500047447R01MH107418ERC CoG PROSOCIAL 681632U54MD013368R01MH107441NSF‐2018‐1826773R305A1601262018‐1288‐13R01 DA039923R56MH111700681632R01 MH107441Teresi GICavanagh CDahl REDziura SLRoy AKMullins JLRose AJRote WMMichalska KJRedcay EBarendse MEAFlannery JDvorsky MRAristizabal MBreaux RBecker SPMagis-Weinberg LNadel HPorter BMDennis-Tiwary TAHo TCTelzer EHPfeifer JHBerger EThomas AGvan de Groep SKilloren SEPrinstein MJLangberg JMChurch JALarguinho TLCampione-Barr NCrone EASweijen SWfalseLongitudinal Change in Adolescent Depression and Anxiety Symptoms from before to during the COVID-19 Pandemic.This study aimed to examine changes in depression and anxiety symptoms from before to during the first 6 months of the COVID-19 pandemic in a sample of 1,339 adolescents (9-18 years old, 59% female) from three countries. We also examined if age, race/ethnicity, disease burden, or strictness of government restrictions moderated change in symptoms. Data from 12 longitudinal studies (10 U.S., 1 Netherlands, 1 Peru) were combined. Linear mixed effect models showed that depression, but not anxiety, symptoms increased significantly (median increase = 28%). The most negative mental health impacts were reported by multiracial adolescents and those under 'lockdown' restrictions. Policy makers need to consider these impacts by investing in ways to support adolescents' mental health during the pandem2022-01-01T00:00:00Z2022 Jul2025-04-19T22:55:50.677Z2025-02-19T04:53:53.638ZS-EPMC93499543579931110.1111/jora.12781