{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hoenigl M"],"funding":["U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID)","NOVA | Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa","U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases","NIAID NIH HHS","EC | Horizon 2020 Framework Programme"],"pagination":["1127-1140"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9362108"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(8)"],"pubmed_abstract":["Coronavirus disease 2019 (COVID-19)-associated invasive fungal infections are an important complication in a substantial number of critically ill, hospitalized patients with COVID-19. Three groups of fungal pathogens cause co-infections in COVID-19: Aspergillus, Mucorales and Candida species, including Candida auris. Here we review the incidence of COVID-19-associated invasive fungal infections caused by these fungi in low-, middle- and high-income countries. By evaluating the epidemiology, clinical risk factors, predisposing features of the host environment and immunological mechanisms that underlie the pathogenesis of these co-infections, we set the scene for future research and development of clinical guidance."],"journal":["Nature microbiology"],"pubmed_title":["COVID-19-associated fungal infections."],"pmcid":["PMC9362108"],"funding_grant_id":["R01 AI153356","PTDC/SAU-SER/29635/2017","R01AI153356","UIDB/50026/2020 and UIDP/50026/2020","R01AI063503","no. 847507"],"pubmed_authors":["Carvalho A","Goldman GH","Sprute R","Ibrahim AS","Seidel D","Oliverio M","Hoenigl M","Cunha C"],"additional_accession":[]},"is_claimable":false,"name":"COVID-19-associated fungal infections.","description":"Coronavirus disease 2019 (COVID-19)-associated invasive fungal infections are an important complication in a substantial number of critically ill, hospitalized patients with COVID-19. Three groups of fungal pathogens cause co-infections in COVID-19: Aspergillus, Mucorales and Candida species, including Candida auris. Here we review the incidence of COVID-19-associated invasive fungal infections caused by these fungi in low-, middle- and high-income countries. By evaluating the epidemiology, clinical risk factors, predisposing features of the host environment and immunological mechanisms that underlie the pathogenesis of these co-infections, we set the scene for future research and development of clinical guidance.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-04T10:45:01.082Z","creation":"2025-04-04T10:45:01.082Z"},"accession":"S-EPMC9362108","cross_references":{"pubmed":["35918423"],"doi":["10.1038/s41564-022-01172-2"]}}