{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang R"],"funding":["the Sichuan Province Science and Technology Support Program","National Key R&amp;D Program of China","the project of health commission of Sichuan province","Clinical Incubation Program of West China Hospital, SCU","the Technology Innovation Project of Chengdu Science and Technology Bureau","National Natural Science Foundation of China","National Key Research and Development Program of China","Postdoctoral research and Development Fund and Translational medicine fund of West China Hospital","the 1·3·5 project for disciplines of excellence-Clinical Research Incubation Project, West China Hospital, Sichuan University"],"pagination":["3717"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9367315"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(15)"],"pubmed_abstract":["<h4>Background</h4>Vitamin D deficiency is related to increased cancer risk and deaths. However, whether vitamin D supplementation reduces cancer mortality remains unclear, and several randomized controlled trials yield inconsistent results.<h4>Methods</h4>Medline, Embase, and the Cochrane Central Register of Controlled Trials were searched from their inception until 28 June 2022, for randomized controlled trials investigating vitamin D supplementation. Pooled relative risks (RRs) and their 95% confidence intervals (CIs) were estimated. Trials with vitamin D supplementation combined with calcium supplementation versus placebo alone and recruiting participants with cancer at baseline were excluded in the present study.<h4>Results</h4>This study included 12 trials with a total of 72,669 part"],"journal":["Cancers"],"pubmed_title":["Association between Vitamin D Supplementation and Cancer Mortality: A Systematic Review and Meta-Analysis."],"pmcid":["PMC9367315"],"funding_grant_id":["2021YFSY008, 2020YFS0276, 2020YFS0490","2021YFE0206600","2020HXBH119 and CGZH19002","2019-YF05-00459-SN","2018HXFU008","81672386","2018YFA0108604","19PJ003","21HXFH046"],"pubmed_authors":["Peng X","Xu P","Fang F","He L","Yu J","Zhang R","Hai Y","Wang J","Liu Z","Chong W","He Y","Zhang Y","Pei Y"],"additional_accession":[]},"is_claimable":false,"name":"Association between Vitamin D Supplementation and Cancer Mortality: A Systematic Review and Meta-Analysis.","description":"<h4>Background</h4>Vitamin D deficiency is related to increased cancer risk and deaths. However, whether vitamin D supplementation reduces cancer mortality remains unclear, and several randomized controlled trials yield inconsistent results.<h4>Methods</h4>Medline, Embase, and the Cochrane Central Register of Controlled Trials were searched from their inception until 28 June 2022, for randomized controlled trials investigating vitamin D supplementation. Pooled relative risks (RRs) and their 95% confidence intervals (CIs) were estimated. Trials with vitamin D supplementation combined with calcium supplementation versus placebo alone and recruiting participants with cancer at baseline were excluded in the present study.<h4>Results</h4>This study included 12 trials with a total of 72,669 part","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jul","modification":"2025-04-19T22:57:20.774Z","creation":"2025-02-19T03:32:02.91Z"},"accession":"S-EPMC9367315","cross_references":{"pubmed":["35954381"],"doi":["10.3390/cancers14153717"]}}