{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kempf K"],"funding":["Almased (Germany)","Almased"],"pagination":["3161"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9370463"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(15)"],"pubmed_abstract":["While obesity impairs health-related quality of life (HRQOL), lifestyle interventions targeting weight reduction have been effective in improving HRQOL. Therefore, we hypothesised that a meal replacement-based lifestyle intervention, which has been shown to successfully reduce weight, would also improve HRQOL more effectively than a lifestyle intervention alone. In the international, multicenter, randomised-controlled ACOORH-trial (Almased-Concept-against- Overweight-and-Obesity-and-Related-Health-Risk), overweight or obese participants with elevated risk for metabolic syndrome (<i>n</i> = 463) were randomised into two groups. Both groups received telemonitoring devices and nutritional advice. The intervention group additionally used a protein-rich, low-glycaemic meal replacement for 6 mon"],"journal":["Nutrients"],"pubmed_title":["High-Protein, Low-Glycaemic Meal Replacement Improves Physical Health-Related Quality of Life in High-Risk Persons for Metabolic Syndrome-A Subanalysis of the Randomised-Controlled ACOORH Trial."],"pmcid":["PMC9370463"],"funding_grant_id":["98184"],"pubmed_authors":["Braumann KM","Schenkenberger I","Banzer W","On Behalf Of The Acoorh Study Group","Schaller N","Rohling M","Halle M","Predel HG","Kempf K","Tan S","Toplak H","Martin S","Berg A","McCarthy D"],"additional_accession":[]},"is_claimable":false,"name":"High-Protein, Low-Glycaemic Meal Replacement Improves Physical Health-Related Quality of Life in High-Risk Persons for Metabolic Syndrome-A Subanalysis of the Randomised-Controlled ACOORH Trial.","description":"While obesity impairs health-related quality of life (HRQOL), lifestyle interventions targeting weight reduction have been effective in improving HRQOL. Therefore, we hypothesised that a meal replacement-based lifestyle intervention, which has been shown to successfully reduce weight, would also improve HRQOL more effectively than a lifestyle intervention alone. In the international, multicenter, randomised-controlled ACOORH-trial (Almased-Concept-against- Overweight-and-Obesity-and-Related-Health-Risk), overweight or obese participants with elevated risk for metabolic syndrome (<i>n</i> = 463) were randomised into two groups. Both groups received telemonitoring devices and nutritional advice. The intervention group additionally used a protein-rich, low-glycaemic meal replacement for 6 mon","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jul","modification":"2025-04-04T10:45:18.415Z","creation":"2025-02-19T03:32:23.418Z"},"accession":"S-EPMC9370463","cross_references":{"pubmed":["35956337"],"doi":["10.3390/nu14153161"]}}