biostudies-literatureAbubakar ASThe project of Agricultural Science and Technology Innovation Project of the Chinese Academy of Agricultural ScienceChina Agricultural Research SystemThe Central Public-interest Scientific Institution Basal Research Fund1964https://www.ebi.ac.uk/biostudies/studies/S-EPMC9370764biostudies-literatureUnknown11(15)<i>Apocynum hendersonii is</i> a traditional medicinal plant used primarily as tea. It has a potential health benefit from its rich bioactive substances. This study investigated the reactivity of solvents of different polarities (ethanol, ethyl acetate, n-hexane, methanol, and water) extracts of the <i>A. hendersonii</i> leaf. The phytochemical composition of the extracts was evaluated using a Fourier Transform Infrared spectrophotometer (FT-IR), Gas Chromatography-Mass Spectrometry (GC-MS), UHPLC-MS, and Higher Performance Liquid Chromatography (HPLC). The result revealed the presence of medicinally important bioactive constituents, including phenols, flavonoids, and polysaccharides. Methanol extracts exhibited the highest flavonoid contents (20.11 ± 0.85 mg QE/g DW) and the second-highesPlants (Basel, Switzerland)Phytochemical Composition, Antioxidant, Antibacterial, and Enzyme Inhibitory Activities of Various Organic Extracts from <i>Apocynum hendersonii</i> (Hook.f.) Woodson.PMC9370764Y2019XK15-03CAAS-ASTIP-IBFC04CARS-16- E03Chen PChen KYu CChen JFeng XHuang XGao GWang XBirhanie ZMZhu AAbubakar ASfalsePhytochemical Composition, Antioxidant, Antibacterial, and Enzyme Inhibitory Activities of Various Organic Extracts from <i>Apocynum hendersonii</i> (Hook.f.) Woodson.<i>Apocynum hendersonii is</i> a traditional medicinal plant used primarily as tea. It has a potential health benefit from its rich bioactive substances. This study investigated the reactivity of solvents of different polarities (ethanol, ethyl acetate, n-hexane, methanol, and water) extracts of the <i>A. hendersonii</i> leaf. The phytochemical composition of the extracts was evaluated using a Fourier Transform Infrared spectrophotometer (FT-IR), Gas Chromatography-Mass Spectrometry (GC-MS), UHPLC-MS, and Higher Performance Liquid Chromatography (HPLC). The result revealed the presence of medicinally important bioactive constituents, including phenols, flavonoids, and polysaccharides. Methanol extracts exhibited the highest flavonoid contents (20.11 ± 0.85 mg QE/g DW) and the second-highes2022-01-01T00:00:00Z2022 Jul2025-04-18T15:48:20.452Z2025-02-19T03:32:23.021ZS-EPMC93707643595643910.3390/plants11151964