biostudies-literatureWilliamson ENIHR Applied Research Collaboration Oxford and Thames Valley at Oxford Health NHS Foundation TrustNational Institute for Health Research (NIHR)1654-1664https://www.ebi.ac.uk/biostudies/studies/S-EPMC9373932biostudies-literatureUnknown77(8)<h4>Background</h4>Neurogenic claudication (NC) is a debilitating spinal condition affecting older adults' mobility and quality of life.<h4>Methods</h4>A randomized controlled trial of 438 participants evaluated the effectiveness of a physical and psychological group intervention (BOOST program) compared to physiotherapy assessment and tailored advice (best practice advice [BPA]) for older adults with NC. Participants were identified from spinal clinics (community and secondary care) and general practice records and randomized 2:1 to the BOOST program or BPA. The primary outcome was the Oswestry Disability Index (ODI) at 12 months. Data were also collected at 6 months. Other outcomes included ODI walking item, 6-minute walk test (6MWT), and falls. The primary analysis was intention-to-treaThe journals of gerontology. Series A, Biological sciences and medical sciencesThe Clinical Effectiveness of a Physiotherapy Delivered Physical and Psychological Group Intervention for Older Adults With Neurogenic Claudication: The BOOST Randomized Controlled Trial.PMC9373932NF-SI-0616-10103PTC-RP-PG-0213-20002ICA-CL-2017-03-015NIHR202402Torgerson DMorris ALamb SEHutchinson CFairbank JCMcCabe CWard LTaylor SHansen ZBarker KLPetrou SDutton SJConway OTurner EWatson JMallen CDWilliamson EBruce JMarian IRBearne LFrench DPRogers DBOOST Research GroupNicolson PJAArden JComer CHewitt CSlack MGarrett ASackley CMaredza MBoniface GFitch JGagen RForster ACollins GGriffith FfalseThe Clinical Effectiveness of a Physiotherapy Delivered Physical and Psychological Group Intervention for Older Adults With Neurogenic Claudication: The BOOST Randomized Controlled Trial.<h4>Background</h4>Neurogenic claudication (NC) is a debilitating spinal condition affecting older adults' mobility and quality of life.<h4>Methods</h4>A randomized controlled trial of 438 participants evaluated the effectiveness of a physical and psychological group intervention (BOOST program) compared to physiotherapy assessment and tailored advice (best practice advice [BPA]) for older adults with NC. Participants were identified from spinal clinics (community and secondary care) and general practice records and randomized 2:1 to the BOOST program or BPA. The primary outcome was the Oswestry Disability Index (ODI) at 12 months. Data were also collected at 6 months. Other outcomes included ODI walking item, 6-minute walk test (6MWT), and falls. The primary analysis was intention-to-trea2022-01-01T00:00:00Z2022 Aug2026-03-31T11:26:51.383Z2025-04-05T18:44:58.24ZS-EPMC93739323527902510.1093/gerona/glac063