biostudies-literatureUnknown316Douplat MHospices Civils de Lyon<h4>Study objective</h4>Assess the changes in anxiety, depression, and stress levels over time and identify risk factors among healthcare workers in French emergency departments (EDs) during the first COVID-19 outbreak.<h4>Method</h4>A prospective, multicenter study was conducted in 4 EDs and an emergency medical service (SAMU). During 3 months, participants completed fortnightly questionnaires to assess anxiety, depression, and stress using the Hospital Anxiety and Depression and the Chamoux-Simard scale. The changes in anxiety, depression, and stress levels over time were modelled by a linear mixed model including a period effect and a continuous time effect within periods.<h4>Results</h4>A total of 211 respondents (43.5 %) completed the survey at inclusion. There was a decrease in mean Journal of affective disorders194-200https://www.ebi.ac.uk/biostudies/studies/S-EPMC9376978biostudies-literatureChanges over time in anxiety, depression, and stress symptoms among healthcare workers in French emergency departments during the first COVID-19 outbreak.PMC9376978Douplat MSubtil FMazza SDurand GNohales LTazarourte KJacquin LHernu RTermoz APotinet VHaesebaert JBerthiller JfalseChanges over time in anxiety, depression, and stress symptoms among healthcare workers in French emergency departments during the first COVID-19 outbreak.<h4>Study objective</h4>Assess the changes in anxiety, depression, and stress levels over time and identify risk factors among healthcare workers in French emergency departments (EDs) during the first COVID-19 outbreak.<h4>Method</h4>A prospective, multicenter study was conducted in 4 EDs and an emergency medical service (SAMU). During 3 months, participants completed fortnightly questionnaires to assess anxiety, depression, and stress using the Hospital Anxiety and Depression and the Chamoux-Simard scale. The changes in anxiety, depression, and stress levels over time were modelled by a linear mixed model including a period effect and a continuous time effect within periods.<h4>Results</h4>A total of 211 respondents (43.5 %) completed the survey at inclusion. There was a decrease in mean 2022-01-01T00:00:00Z2022 Nov2026-05-28T04:37:11.254Z2025-02-19T04:38:34.795ZS-EPMC93769783598162610.1016/j.jad.2022.08.028