biostudies-literatureAshamo AYFIC NIH HHSe0273012https://www.ebi.ac.uk/biostudies/studies/S-EPMC9377616biostudies-literatureUnknown17(8)<h4>Background</h4>Various reports suggested that pre-existing medical illnesses, including hypertension and other demographic, clinical, and laboratory factors, could pose an increased risk of disease severity and mortality among COVID-19 patients. This study aimed to assess the relation of hypertension and other factors to the severity of COVID-19 pneumonia in patients discharged from Eka Kotebe Hospital in June-September, 2020.<h4>Methods</h4>This is a single-center case-control study of 265 adult patients discharged alive or dead, 75 with a course of severe COVID-19 for the cases arm and 190 with the non-severe disease for the control arm. Three age and sex-matched controls were selected randomly for each patient on the case arm. Chi-square, multivariable binary logistic regression, anPloS oneAssessment of hypertension and other factors associated with the severity of disease in COVID-19 pneumonia, Addis Ababa, Ethiopia: A case-control study.PMC9377616D43 TW009127Ashamo AYKebede DEtissa EKPetrose ADeyessa NBekele AYusuf HGebreyes THaisch DHaile TSchluger NWfalseAssessment of hypertension and other factors associated with the severity of disease in COVID-19 pneumonia, Addis Ababa, Ethiopia: A case-control study.<h4>Background</h4>Various reports suggested that pre-existing medical illnesses, including hypertension and other demographic, clinical, and laboratory factors, could pose an increased risk of disease severity and mortality among COVID-19 patients. This study aimed to assess the relation of hypertension and other factors to the severity of COVID-19 pneumonia in patients discharged from Eka Kotebe Hospital in June-September, 2020.<h4>Methods</h4>This is a single-center case-control study of 265 adult patients discharged alive or dead, 75 with a course of severe COVID-19 for the cases arm and 190 with the non-severe disease for the control arm. Three age and sex-matched controls were selected randomly for each patient on the case arm. Chi-square, multivariable binary logistic regression, an2022-01-01T00:00:00Z20222025-04-22T11:01:02.049Z2025-04-05T23:48:08.73ZS-EPMC93776163596959010.1371/journal.pone.0273012