biostudies-literatureUnknown12(1)El-Samad LWith the evolution of nanostructure materials, silver nanoparticles (Ag-NPs) emerged as the predominantly exploited nanomaterial in multifarious sectors due to their versatile properties. Along with the heightening applications of Ag-NPs, however, there is increasing concern over their indubitable toxicity towards the ecosystem, which indeed affects surrounding organisms and human health. In this study, we evaluated the detrimental effects of Ag-NPs in relation to Egyptian wild female beetles, Blaps polychresta, after injection with a single dose of Ag-NPs at different doses and monitoring for 30 days to determine the sublethal dose. Accordingly, the sublethal dose revealed the lowest negative influence was found at 0.03 mg/g body weight. The adverse impacts of Ag-NPs on the ovaries of femScientific reportshttps://www.ebi.ac.uk/biostudies/studies/S-EPMC9381597biostudies-literatureInsights into Ag-NPs-mediated pathophysiology and ultrastructural aberrations in ovarian tissues of darkling beetlesPMC9381597El-Samad LHassan MAbdul Aziz KEl Wakil AHussein HRadwan EBakr NEl-Ashram SfalseInsights into Ag-NPs-mediated pathophysiology and ultrastructural aberrations in ovarian tissues of darkling beetlesWith the evolution of nanostructure materials, silver nanoparticles (Ag-NPs) emerged as the predominantly exploited nanomaterial in multifarious sectors due to their versatile properties. Along with the heightening applications of Ag-NPs, however, there is increasing concern over their indubitable toxicity towards the ecosystem, which indeed affects surrounding organisms and human health. In this study, we evaluated the detrimental effects of Ag-NPs in relation to Egyptian wild female beetles, Blaps polychresta, after injection with a single dose of Ag-NPs at different doses and monitoring for 30 days to determine the sublethal dose. Accordingly, the sublethal dose revealed the lowest negative influence was found at 0.03 mg/g body weight. The adverse impacts of Ag-NPs on the ovaries of fem2022-01-01T00:00:00Z2022 Jan2025-04-04T11:33:16.77Z2025-02-19T05:05:52.034ZS-EPMC9381597