biostudies-literatureUnknown17(1)Amiot A<h4>Background and aims</h4>There are concerns regarding the potential impact of the COVID-19 outbreak on patients with inflammatory bowel disease [IBD]. We report on the impact of the COVID-19 outbreak in a European prospective cohort study of patients with IBD.<h4>Patients and methods</h4>We prospectively collected data from 5457 patients with IBD nested in the ongoing I-CARE project and still followed up in April 2020, with monthly online monitoring of clinical activity, treatment, imaging and endoscopy. Investigators were also contacted to report incidental cases.<h4>Results</h4>In total, 233 [4.3%] reported COVID-19 and 12 [0.2%] severe COVID-19, with no COVID-19 deaths. The risk of COVID-19 in patients with IBD was not increased compared to the general population (standardized incideJournal of Crohn's & colitis37-48https://www.ebi.ac.uk/biostudies/studies/S-EPMC9384408biostudies-literatureThe Impact of COVID-19 on Patients with IBD in a Prospective European Cohort Study.PMC9384408Mazhar ZMantzaris GTrang CFung MAbitbol VGordon JDubois PButterworth JLaharie DGornet JMFilippi JHart ADe Vos MBiancone LShitrit AVani DAltwegg RStaicu AHebuterne XAvni Biron IPreston CMathieu NZeissig SHasselblatt PPrincipi MBSpeight AKoss KShariq SRahier JFCorless LI-CARE collaborator groupShenoy AElphick DKopylov UBonnet JLowenberg MCostes LRoblin XD’inca RFarkas KYanai HBurisch JLocher CNahon SFranchimont DNachury MGhosh DLandy JSiegmund BBaert FVuitton LParkes GLimdi JFumery MBlanc PMagro FSonwalkar SValats JCMaaser CPineton De Chambrun GHeluwaert FO’morain CNancey SGilletta CMichalopoulos GDallal HKarmiris KRamadas ABaburajan BAmiot ADomenech EAbouda GHobday DZallot CWesley ESingh SBarberis CShenderey RViazis NBamias GMacaigne GDewitte MEder PCastiglione FTsai HSzepes ZTheodoropoulou ANakad AReimund JMBouguen GBellaiche GPelletier ALReenears CPeyrin-Biroulet LMichiels CLobaton TDoherty GPhillips ABurton JGangi MKirchgesner JBeaugerie LClayton EPedersen NBell AOrlando ASmith KCalabrese EMolnar TKaassis MfalseThe Impact of COVID-19 on Patients with IBD in a Prospective European Cohort Study.<h4>Background and aims</h4>There are concerns regarding the potential impact of the COVID-19 outbreak on patients with inflammatory bowel disease [IBD]. We report on the impact of the COVID-19 outbreak in a European prospective cohort study of patients with IBD.<h4>Patients and methods</h4>We prospectively collected data from 5457 patients with IBD nested in the ongoing I-CARE project and still followed up in April 2020, with monthly online monitoring of clinical activity, treatment, imaging and endoscopy. Investigators were also contacted to report incidental cases.<h4>Results</h4>In total, 233 [4.3%] reported COVID-19 and 12 [0.2%] severe COVID-19, with no COVID-19 deaths. The risk of COVID-19 in patients with IBD was not increased compared to the general population (standardized incide2023-01-01T00:00:00Z2023 Jan2026-05-09T19:38:03.613Z2025-04-04T13:55:43.496ZS-EPMC93844083576763910.1093/ecco-jcc/jjac091