{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["107(9)"],"submitter":["Jalleh RJ"],"pubmed_abstract":["<h4>Context</h4>The relationships of gastric emptying (GE) with the glycemic response at 120 minutes, glucagon-like peptide-1 (GLP-1), and insulin secretion following a glucose load in type 2 diabetes (T2D) are uncertain.<h4>Objective</h4>We evaluated the relationship of plasma glucose, GLP-1, and insulin secretion with GE of a 75-g oral glucose load in T2D.<h4>Design</h4>Single-center, cross-sectional, post hoc analysis.<h4>Setting</h4>Institutional research center.<h4>Participants</h4>43 individuals with T2D age 65.6 ± 1.1 years, hemoglobin A1c 7.2 ± 1.0%, median duration of diabetes 5 years managed by diet and/or metformin.<h4>Intervention</h4>Participants consumed the glucose drink radiolabeled with 99mTc-phytate colloid following an overnight fast. GE (scintigraphy), plasma glucose, G"],"journal":["The Journal of clinical endocrinology and metabolism"],"pagination":["e3850-e3856"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9387705"],"repository":["biostudies-literature"],"pubmed_title":["Relationships of Glucose, GLP-1, and Insulin Secretion With Gastric Emptying After a 75-g Glucose Load in Type 2 Diabetes."],"pmcid":["PMC9387705"],"pubmed_authors":["Marathe CS","Horowitz M","Jones KL","Jalleh RJ","Wu T","Rayner CK"],"additional_accession":[]},"is_claimable":false,"name":"Relationships of Glucose, GLP-1, and Insulin Secretion With Gastric Emptying After a 75-g Glucose Load in Type 2 Diabetes.","description":"<h4>Context</h4>The relationships of gastric emptying (GE) with the glycemic response at 120 minutes, glucagon-like peptide-1 (GLP-1), and insulin secretion following a glucose load in type 2 diabetes (T2D) are uncertain.<h4>Objective</h4>We evaluated the relationship of plasma glucose, GLP-1, and insulin secretion with GE of a 75-g oral glucose load in T2D.<h4>Design</h4>Single-center, cross-sectional, post hoc analysis.<h4>Setting</h4>Institutional research center.<h4>Participants</h4>43 individuals with T2D age 65.6 ± 1.1 years, hemoglobin A1c 7.2 ± 1.0%, median duration of diabetes 5 years managed by diet and/or metformin.<h4>Intervention</h4>Participants consumed the glucose drink radiolabeled with 99mTc-phytate colloid following an overnight fast. GE (scintigraphy), plasma glucose, G","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-05T11:27:38.529Z","creation":"2025-04-05T11:27:38.529Z"},"accession":"S-EPMC9387705","cross_references":{"pubmed":["35608823"],"doi":["10.1210/clinem/dgac330"]}}