{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Garfinkle R"],"funding":["Canadian Association of General Surgeons","Society of American Gastrointestinal and Endoscopic Surgeons"],"pagination":["3934-3943"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9390101"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["37(5)"],"pubmed_abstract":["<h4>Introduction</h4>The objective of this study was to evaluate the impact of preoperative bowel stimulation on the development of postoperative ileus (POI) after loop ileostomy closure.<h4>Methods</h4>This was a multicenter, randomized controlled trial (NCT025596350) including adult (≥ 18 years old) patients who underwent elective loop ileostomy closure at 7 participating hospitals. Participants were randomly assigned (1:1) using a centralized computer-generated sequence with block randomization to either preoperative bowel stimulation or no stimulation (control group). Bowel stimulation consisted of 10 outpatient sessions within the 3 weeks prior to ileostomy closure and was performed by trained Enterostomal Therapy nurses. The primary outcome was POI, defined as an intolerance to oral "],"journal":["Surgical endoscopy"],"pubmed_title":["Bowel stimulation before loop ileostomy closure to reduce postoperative ileus: a multicenter, single-blinded, randomized controlled trial."],"pmcid":["PMC9390101"],"funding_grant_id":["4692","4689"],"pubmed_authors":["Vasilevsky CA","Lee L","Charlebois P","Faria J","Hameed U","Demian M","Garfinkle R","Herd A","Stein B","Liberman AS","Nisbet S","Sabboobeh S","Boutros M","Rajaratnam S","Stotland P","Bowel Stimulation Research Collaborative","Morin N","Chadi SA","Jarvis J","Quereshy F","Bhama AR","Demyttenaere S","Tataryn D","Feinberg S","Hulme-Moir M","Quintin L","Hayden DM","Samuel L","Hotakorzian N","Ghitulescu G","Moot A","Moon J"],"additional_accession":[]},"is_claimable":false,"name":"Bowel stimulation before loop ileostomy closure to reduce postoperative ileus: a multicenter, single-blinded, randomized controlled trial.","description":"<h4>Introduction</h4>The objective of this study was to evaluate the impact of preoperative bowel stimulation on the development of postoperative ileus (POI) after loop ileostomy closure.<h4>Methods</h4>This was a multicenter, randomized controlled trial (NCT025596350) including adult (≥ 18 years old) patients who underwent elective loop ileostomy closure at 7 participating hospitals. Participants were randomly assigned (1:1) using a centralized computer-generated sequence with block randomization to either preoperative bowel stimulation or no stimulation (control group). Bowel stimulation consisted of 10 outpatient sessions within the 3 weeks prior to ileostomy closure and was performed by trained Enterostomal Therapy nurses. The primary outcome was POI, defined as an intolerance to oral ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2026-05-31T16:07:32.258Z","creation":"2025-02-19T01:27:30.325Z"},"accession":"S-EPMC9390101","cross_references":{"pubmed":["35984521"],"doi":["10.1007/s00464-022-09510-5"]}}