biostudies-literatureContreras JDNICHD NIH HHSNIEHS NIH HHSNational Institutes of HealthBill and Melinda Gates Foundatione1004041https://www.ebi.ac.uk/biostudies/studies/S-EPMC9394830biostudies-literatureUnknown19(8)<h4>Background</h4>Diarrhea and acute respiratory infection (ARI) are leading causes of death in children. The WASH Benefits Bangladesh trial implemented a multicomponent sanitation intervention that led to a 39% reduction in the prevalence of diarrhea among children and a 25% reduction for ARI, measured 1 to 2 years after intervention implementation. We measured longer-term intervention effects on these outcomes between 1 to 3.5 years after intervention implementation, including periods with differing intensity of behavioral promotion.<h4>Methods and findings</h4>WASH Benefits Bangladesh was a cluster-randomized controlled trial of water, sanitation, hygiene, and nutrition interventions (NCT01590095). The sanitation intervention included provision of or upgrades to improved latrines, saniPLoS medicineEvaluation of an on-site sanitation intervention against childhood diarrhea and acute respiratory infection 1 to 3.5 years after implementation: Extended follow-up of a cluster-randomized controlled trial in rural Bangladesh.PMC93948300PPGD759R01 HD078912P30 ES025128R01HD078912Hubbard AELuby SPContreras JDBenjamin-Chung JColford JMMertens AArnold BFIslam MUnicomb LPickering AJRahman MErcumen AfalseEvaluation of an on-site sanitation intervention against childhood diarrhea and acute respiratory infection 1 to 3.5 years after implementation: Extended follow-up of a cluster-randomized controlled trial in rural Bangladesh.<h4>Background</h4>Diarrhea and acute respiratory infection (ARI) are leading causes of death in children. The WASH Benefits Bangladesh trial implemented a multicomponent sanitation intervention that led to a 39% reduction in the prevalence of diarrhea among children and a 25% reduction for ARI, measured 1 to 2 years after intervention implementation. We measured longer-term intervention effects on these outcomes between 1 to 3.5 years after intervention implementation, including periods with differing intensity of behavioral promotion.<h4>Methods and findings</h4>WASH Benefits Bangladesh was a cluster-randomized controlled trial of water, sanitation, hygiene, and nutrition interventions (NCT01590095). The sanitation intervention included provision of or upgrades to improved latrines, sani2022-01-01T00:00:00Z2022 Aug2026-05-31T16:07:53.653Z2025-02-19T01:28:19.494ZS-EPMC93948303593952010.1371/journal.pmed.1004041