biostudies-literatureXu SDescartes Centre voor Wetenschapsgeschiedenis en Wetenschapsfilosofie, Universiteit UtrechtEuropean Research CouncilEU Graphene FlagshipCoordination Networks: Building Blocks for Functional Sys-temsMaterials Chemistry ConsortiumH2020-MSCA-ITNe202202492https://www.ebi.ac.uk/biostudies/studies/S-EPMC9401016biostudies-literatureUnknown61(21)Vinylene-linked two-dimensional conjugated covalent organic frameworks (V-2D-COFs), belonging to the class of two-dimensional conjugated polymers, have attracted increasing attention due to their extended π-conjugation over the 2D backbones associated with high chemical stability. The Knoevenagel polycondensation has been demonstrated as a robust synthetic method to provide cyano (CN)-substituted V-2D-COFs with unique optoelectronic, magnetic, and redox properties. Despite the successful synthesis, it remains elusive for the relevant polymerization mechanism, which leads to relatively low crystallinity and poor reproducibility. In this work, we demonstrate the novel synthesis of CN-substituted V-2D-COFs via the combination of Knoevenagel polycondensation and water-assisted dynamic Michael-Angewandte Chemie (International ed. in English)Combination of Knoevenagel Polycondensation and Water-Assisted Dynamic Michael-Addition-Elimination for the Synthesis of Vinylene-Linked 2D Covalent Organic Frameworks.PMC9401016GrapheneCore3; No. 881603813036EP/T022213SPP 1928, COORNET417590517819698Liao ZFabozzi FGPastoetter DLDianat AFeng XRichter MFu YPark SWLiu YXu SCuniberti GAddicoat MAHecht SfalseCombination of Knoevenagel Polycondensation and Water-Assisted Dynamic Michael-Addition-Elimination for the Synthesis of Vinylene-Linked 2D Covalent Organic Frameworks.Vinylene-linked two-dimensional conjugated covalent organic frameworks (V-2D-COFs), belonging to the class of two-dimensional conjugated polymers, have attracted increasing attention due to their extended π-conjugation over the 2D backbones associated with high chemical stability. The Knoevenagel polycondensation has been demonstrated as a robust synthetic method to provide cyano (CN)-substituted V-2D-COFs with unique optoelectronic, magnetic, and redox properties. Despite the successful synthesis, it remains elusive for the relevant polymerization mechanism, which leads to relatively low crystallinity and poor reproducibility. In this work, we demonstrate the novel synthesis of CN-substituted V-2D-COFs via the combination of Knoevenagel polycondensation and water-assisted dynamic Michael-2022-01-01T00:00:00Z2022 May2026-05-28T01:12:01.161Z2024-10-18T22:31:17.152ZS-EPMC94010163525333610.1002/anie.202202492