biostudies-literatureUnknown61(28)Alessandri IThe photodimerization of 4-aminothiophenol (PATP) into 4,4'-dimercaptobenzene (DMAB) has been extensively utilized as a paradigm reaction to probe the role of surface plasmons in nanoparticle-mediated light-driven processes. Here I report the first observation of the PATP-to-DMAB photoreaction in the absence of any plasmonic mediators. The reaction was observed to occur with different kinetics either for PATP adsorbed on non-plasmonic nanoparticles (TiO₂ , ZnO, SiO₂ ) or deposited as macroscopic droplets. Confocal microRaman spectroscopy enabled to investigate the reaction progress in different plasmon-free contexts, either aerobic or anaerobic, suggesting a new interpretation of the photodimerization process, based on direct laser-induced activation of singlet oxygen species. These results provide new insights in light-driven redox processes, elucidating the role of sample morphology, light and oxygen.Angewandte Chemie (International ed. in English)e202205013https://www.ebi.ac.uk/biostudies/studies/S-EPMC9401036biostudies-literature4-Aminothiophenol Photodimerization Without Plasmons.PMC9401036Alessandri Ifalse4-Aminothiophenol Photodimerization Without Plasmons.The photodimerization of 4-aminothiophenol (PATP) into 4,4'-dimercaptobenzene (DMAB) has been extensively utilized as a paradigm reaction to probe the role of surface plasmons in nanoparticle-mediated light-driven processes. Here I report the first observation of the PATP-to-DMAB photoreaction in the absence of any plasmonic mediators. The reaction was observed to occur with different kinetics either for PATP adsorbed on non-plasmonic nanoparticles (TiO₂ , ZnO, SiO₂ ) or deposited as macroscopic droplets. Confocal microRaman spectroscopy enabled to investigate the reaction progress in different plasmon-free contexts, either aerobic or anaerobic, suggesting a new interpretation of the photodimerization process, based on direct laser-induced activation of singlet oxygen species. These results provide new insights in light-driven redox processes, elucidating the role of sample morphology, light and oxygen.2022-01-01T00:00:00Z2022 Jul2025-06-01T01:32:25.863Z2025-06-01T01:32:25.863ZS-EPMC94010363553297410.1002/anie.202205013