{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bychek R"],"funding":["European Research Council","HORIZON EUROPE European Research Council"],"pagination":["e202205103"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9401599"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["61(29)"],"pubmed_abstract":["After more than 20 years of trials, a practical scalable approach to fluoro-substituted bicyclo[1.1.1]pentanes (F-BCPs) has been developed. The physicochemical properties of the F-BCPs have been studied, and the core was incorporated into the structure of the anti-inflammatory drug Flurbiprofen in place of the fluorophenyl ring."],"journal":["Angewandte Chemie (International ed. in English)"],"pubmed_title":["A Practical and Scalable Approach to Fluoro-Substituted Bicyclo[1.1.1]pentanes."],"pmcid":["PMC9401599"],"funding_grant_id":["101000893"],"pubmed_authors":["Mykhailiuk PK","Bychek R"],"additional_accession":[]},"is_claimable":false,"name":"A Practical and Scalable Approach to Fluoro-Substituted Bicyclo[1.1.1]pentanes.","description":"After more than 20 years of trials, a practical scalable approach to fluoro-substituted bicyclo[1.1.1]pentanes (F-BCPs) has been developed. The physicochemical properties of the F-BCPs have been studied, and the core was incorporated into the structure of the anti-inflammatory drug Flurbiprofen in place of the fluorophenyl ring.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jul","modification":"2025-06-01T01:32:28.548Z","creation":"2025-06-01T01:32:28.548Z"},"accession":"S-EPMC9401599","cross_references":{"pubmed":["35638404"],"doi":["10.1002/anie.202205103"]}}