{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(9)"],"submitter":["Meng N"],"pubmed_abstract":["<h4>Background</h4>Noninvasive assessment of programmed death-ligand 1 (PD-L1) expression status in non-small cell lung cancer (NSCLC) is necessary. This study arm to investigate the value of 2-[<sup>18</sup>F]-fluoro-2-deoxy-D-glucose positron emission tomography (<sup>18</sup>F-FDG PET), diffusion-weighted imaging (DWI), intravoxel incoherent motion (IVIM), and amide proton transfer-weighted imaging (APTWI) in the assessment of PD-L1 status in NSCLC.<h4>Methods</h4>This is a prospective diagnostic study. A total of 76 patients with NSCLC underwent chest <sup>18</sup>F-FDG PET/magnetic resonance imaging (MRI). Parameters maximum standardized uptake value (SUV<sub>max</sub>), quantitate the metabolic tumor volume (MTV), total lesion glycolysis (TLG), apparent diffusion coefficient (ADC), d"],"journal":["Quantitative imaging in medicine and surgery"],"pagination":["4474-4487"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9403585"],"repository":["biostudies-literature"],"pubmed_title":["Sensitivity and specificity of amide proton transfer-weighted imaging for assessing programmed death-ligand 1 status in non-small cell lung cancer: a comparative study with intravoxel incoherent motion and <sup>18</sup>F-FDG PET."],"pmcid":["PMC9403585"],"pubmed_authors":["Liu H","Wang M","Li X","Yang Y","Fu F","Meng N","Luo Y","Wang Z","Sun J","Feng P","Wu Y","Yuan J"],"additional_accession":[]},"is_claimable":false,"name":"Sensitivity and specificity of amide proton transfer-weighted imaging for assessing programmed death-ligand 1 status in non-small cell lung cancer: a comparative study with intravoxel incoherent motion and <sup>18</sup>F-FDG PET.","description":"<h4>Background</h4>Noninvasive assessment of programmed death-ligand 1 (PD-L1) expression status in non-small cell lung cancer (NSCLC) is necessary. This study arm to investigate the value of 2-[<sup>18</sup>F]-fluoro-2-deoxy-D-glucose positron emission tomography (<sup>18</sup>F-FDG PET), diffusion-weighted imaging (DWI), intravoxel incoherent motion (IVIM), and amide proton transfer-weighted imaging (APTWI) in the assessment of PD-L1 status in NSCLC.<h4>Methods</h4>This is a prospective diagnostic study. A total of 76 patients with NSCLC underwent chest <sup>18</sup>F-FDG PET/magnetic resonance imaging (MRI). Parameters maximum standardized uptake value (SUV<sub>max</sub>), quantitate the metabolic tumor volume (MTV), total lesion glycolysis (TLG), apparent diffusion coefficient (ADC), d","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2025-04-05T12:32:09.848Z","creation":"2024-11-10T06:28:15.055Z"},"accession":"S-EPMC9403585","cross_references":{"pubmed":["36060584"],"doi":["10.21037/qims-22-189"]}}