{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(10)"],"submitter":["Van Mieghem NM"],"pubmed_abstract":["<h4>Importance</h4>In patients with severe aortic valve stenosis at intermediate surgical risk, transcatheter aortic valve replacement (TAVR) with a self-expanding supra-annular valve was noninferior to surgery for all-cause mortality or disabling stroke at 2 years. Comparisons of longer-term clinical and hemodynamic outcomes in these patients are limited.<h4>Objective</h4>To report prespecified secondary 5-year outcomes from the Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI) randomized clinical trial.<h4>Design, setting, and participants</h4>SURTAVI is a prospective randomized, unblinded clinical trial. Randomization was stratified by investigational site and need for revascularization determined by the local heart teams. Patients wit"],"journal":["JAMA cardiology"],"pagination":["1000-1008"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9403849"],"repository":["biostudies-literature"],"pubmed_title":["Self-expanding Transcatheter vs Surgical Aortic Valve Replacement in Intermediate-Risk Patients: 5-Year Outcomes of the SURTAVI Randomized Clinical Trial."],"pmcid":["PMC9403849"],"pubmed_authors":["Edmonson S","Polsani V","Glower D","Little S","Bajwa T","Worgan B","Estrada K","Watanabe C","Nanduri S","Margey R","Rost I","Scheele M","Oplinger J","Todd A","Russell C","Welz A","Plank B","Konopka K","Khalique O","Taboada S","Bavbekova S","Rosenbloom M","Sundararajan J","Ruiter A","White J","White S","Yamasaki H","Yamasaki K","Herder W","Musarra R","Gulati D","Bradbury E","Cardozo M","Temple A","Amrane H","Llosa Cortina JC","Muehlebach G","Santiago L","Lowery M","Lowery R","Gulati R","Reul R","Eriksen E","Stader M","Malkin CJ","Barry M","Brinegar P","Rao S","Phuong N","Agarwal 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K","Elijovich L","Wyler von Ballmoos M","Mazzurco S","Velazquez E","Kirkland L","Kachoris J","Mardell S","Hettich I","Medina Fernandez M","Bremer K","Park S","Misra A","Khella S","Hoff S","Vannan M","Guerin D","Long D","Swenson C","Newbold S","Liam D","Willhide J","Esposito R","Siller K","Malasana G","Morin C","Brunetti D","Purrington E","Punzalan R","Staniloae C","Terluin H","Faheem O","Winker T","Streib C","Mueller-Kronast N","Garimella S","Gonzales M","Gada H","Beyersdorf F","McGargle R","Campbell D","Iyengar P","Volpi J"],"additional_accession":[]},"is_claimable":false,"name":"Self-expanding Transcatheter vs Surgical Aortic Valve Replacement in Intermediate-Risk Patients: 5-Year Outcomes of the SURTAVI Randomized Clinical Trial.","description":"<h4>Importance</h4>In patients with severe aortic valve stenosis at intermediate surgical risk, transcatheter aortic valve replacement (TAVR) with a self-expanding supra-annular valve was noninferior to surgery for all-cause mortality or disabling stroke at 2 years. Comparisons of longer-term clinical and hemodynamic outcomes in these patients are limited.<h4>Objective</h4>To report prespecified secondary 5-year outcomes from the Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI) randomized clinical trial.<h4>Design, setting, and participants</h4>SURTAVI is a prospective randomized, unblinded clinical trial. Randomization was stratified by investigational site and need for revascularization determined by the local heart teams. Patients wit","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2026-06-06T01:13:01.626Z","creation":"2025-04-04T20:06:56.074Z"},"accession":"S-EPMC9403849","cross_references":{"pubmed":["36001335"],"doi":["10.1001/jamacardio.2022.2695"]}}