biostudies-literatureUnknown12(8)Raimondi FProne positioning is frequently used for non-intubated hypoxemic patients with COVID-19, although conclusive evidence is still lacking. The aim of the present study was to investigate whether baseline CT-scans could predict the improvement in oxygenation in COVID-19 related Acute respira-tory syndrome (ARDS) patients when pronated.<h4>Methods</h4>A retrospective study of COVID-19 patients who underwent non-invasive ventilation (NIV) and prone positioning was conducted.<h4>Results</h4>Forty-five patients were included. On average, 50% of the overall lung volume was affected by the disease, as observed in the CT-scans, with ground glass opacities (GGOs) and consolidations accounting for 44% and 4%, respectively. The abnormalities were mainly posterior, as demonstrated by posterior/anterior dDiagnostics (Basel, Switzerland)1848https://www.ebi.ac.uk/biostudies/studies/S-EPMC9406535biostudies-literatureExtent and Distribution of Parenchymal Abnormalities in Baseline CT-Scans Do Not Predict Awake Prone Positioning Response in COVID-19 Related ARDS.PMC9406535Raimondi FBrivio MDi Marco FGritti PSironi SCazzaniga SLorini FLAnnibali SPappacena SMalandrino LBianco ILiggeri NNovelli LBonaffini PAfalseExtent and Distribution of Parenchymal Abnormalities in Baseline CT-Scans Do Not Predict Awake Prone Positioning Response in COVID-19 Related ARDS.Prone positioning is frequently used for non-intubated hypoxemic patients with COVID-19, although conclusive evidence is still lacking. The aim of the present study was to investigate whether baseline CT-scans could predict the improvement in oxygenation in COVID-19 related Acute respira-tory syndrome (ARDS) patients when pronated.<h4>Methods</h4>A retrospective study of COVID-19 patients who underwent non-invasive ventilation (NIV) and prone positioning was conducted.<h4>Results</h4>Forty-five patients were included. On average, 50% of the overall lung volume was affected by the disease, as observed in the CT-scans, with ground glass opacities (GGOs) and consolidations accounting for 44% and 4%, respectively. The abnormalities were mainly posterior, as demonstrated by posterior/anterior d2022-01-01T00:00:00Z2022 Jul2025-04-19T01:37:08.162Z2025-04-07T12:22:25.358ZS-EPMC94065353601019910.3390/diagnostics12081848