biostudies-literatureDemir EScientific and Technological Research Council of Turkey9121https://www.ebi.ac.uk/biostudies/studies/S-EPMC9408976biostudies-literatureUnknown23(16)New insights into the interactions between nanopesticides and edible plants are required in order to elucidate their impacts on human health and agriculture. Nanopesticides include formulations consisting of organic/inorganic nanoparticles. <i>Drosophila melanogaster</i> has become a powerful model in genetic research thanks to its genetic similarity to mammals. This project mainly aimed to generate new evidence for the toxic/genotoxic properties of different nanopesticides (a nanoemulsion (permethrin nanopesticides, 20 ± 5 nm), an inorganic nanoparticle as an active ingredient (copper(II) hydroxide [Cu(OH)₂] nanopesticides, 15 ± 6 nm), a polymer-based nanopesticide (acephate nanopesticides, 55 ± 25 nm), and an inorganic nanoparticle associated with an organic active ingredient International journal of molecular sciencesHazard Assessment of the Effects of Acute and Chronic Exposure to Permethrin, Copper Hydroxide, Acephate, and Validamycin Nanopesticides on the Physiology of <i>Drosophila</i>: Novel Insights into the Cellular Internalization and Biological Effects.PMC9408976119Z208Topel OTurna Demir FKandur MYDemir EDogan MKansız SAkkoyunlu GfalseHazard Assessment of the Effects of Acute and Chronic Exposure to Permethrin, Copper Hydroxide, Acephate, and Validamycin Nanopesticides on the Physiology of <i>Drosophila</i>: Novel Insights into the Cellular Internalization and Biological Effects.New insights into the interactions between nanopesticides and edible plants are required in order to elucidate their impacts on human health and agriculture. Nanopesticides include formulations consisting of organic/inorganic nanoparticles. <i>Drosophila melanogaster</i> has become a powerful model in genetic research thanks to its genetic similarity to mammals. This project mainly aimed to generate new evidence for the toxic/genotoxic properties of different nanopesticides (a nanoemulsion (permethrin nanopesticides, 20 ± 5 nm), an inorganic nanoparticle as an active ingredient (copper(II) hydroxide [Cu(OH)₂] nanopesticides, 15 ± 6 nm), a polymer-based nanopesticide (acephate nanopesticides, 55 ± 25 nm), and an inorganic nanoparticle associated with an organic active ingredient 2022-01-01T00:00:00Z2022 Aug2025-04-18T19:07:08.318Z2024-11-19T16:59:12.763ZS-EPMC94089763601238810.3390/ijms23169121